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Cytosolic beta-Glucosidase/GBA3 Antibody (OTI1F1) [PE/Atto594]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, IHC
Clone
OTI1F1
Clonality
Monoclonal
Host
Mouse
Conjugate
PE/Atto594

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-72100AF350
Alexa Fluor 405
NBP2-72100AF405
Alexa Fluor 488
NBP2-72100AF488
Alexa Fluor 532
NBP2-72100AF532
Alexa Fluor 594
NBP2-72100AF594
Alexa Fluor 647
NBP2-72100AF647
Alexa Fluor 700
NBP2-72100AF700
Alexa Fluor 750
NBP2-72100AF750
Allophycocyanin
NBP2-72100APC
Allophycocyanin/Cy7
NBP2-72100APCCY7
Biotin
NBP2-72100B
CoraFluor 1
NBP2-72100CL1
DyLight 350
NBP2-72100UV
DyLight 405
NBP2-72100V
DyLight 488
NBP2-72100G
DyLight 550
NBP2-72100R
DyLight 594
NBP2-72100DL594
DyLight 650
NBP2-72100C
DyLight 680
NBP2-72100FR
DyLight 755
NBP2-72100IR
FITC
NBP2-72100F
HRP
NBP2-72100H
Janelia Fluor 525
NBP2-72100JF525
Janelia Fluor 549
NBP2-72100JF549
Janelia Fluor 646
NBP2-72100JF646
Janelia Fluor 669
NBP2-72100JF669
PE
NBP2-72100PE
PE/Cy5.5
NBP2-72100PECY55
PE/Cy7
NBP2-72100PECY7
PerCP
NBP2-72100PCP
Unconjugated
NBP2-00521
mFluor Violet 450 SE
NBP2-72100MFV450
mFluor Violet 500 SE
NBP2-72100MFV500
mFluor Violet 610 SE
NBP2-72100MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-00521
Azide and BSA Free
NBP2-72100
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Cytosolic beta-Glucosidase/GBA3 Antibody (OTI1F1) [PE/Atto594] Summary

Immunogen
Recombinant protein fragment corresponding to amino acids 1-150 and 370-469 of human Cytosolic beta-Glucosidase/GBA3 (NP_066024) produced in E.coli.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
GBA3
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Cytosolic beta-Glucosidase/GBA3 Antibody (OTI1F1) [PE/Atto594]

  • CBG
  • CBGL1
  • CBGL1GLUC
  • Cytosolic betaGlucosidase
  • Cytosolic beta-Glucosidase
  • Cytosolic beta-glucosidase-like protein 1
  • EC 3.2.1.21
  • GBA3
  • GLUC
  • glucosidase, beta, acid 3 (cytosolic)
  • klotho-related protein
  • KLrP
  • MGC104276
  • MGC126878

Background

GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol GBA3