Name: Cystathionase Antibody (S51)
Brand: Novus Biologicals
SKU: H00001491-M03
Price: 519 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	Hu, Mu, Rt, PoSpecies Glossary
Applications	WB, ELISA, ICC/IF, IHC
Clone	S51
Clonality	Monoclonal
Host	Mouse
Conjugate	Unconjugated

Description	Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen	CTH (AAH15807, 1 a.a. ~ 405 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MQEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGRSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAAHPPSGSHS
Localization	Cytoplasmic
Specificity	CTH - cystathionase (cystathionine gamma-lyase)
Isotype	IgG1 Kappa
Clonality	Monoclonal
Host	Mouse
Gene	CTH
Purity	IgG purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer	In 1x PBS, pH 7.4
Preservative	No Preservative
Purity	IgG purified

Publications using H00001491-M03	Applications	Species
Wang Y, Huang J, Chen W et al. Dysregulation of cystathionine ?-lyase promotes prostate cancer progression and metastasis. EMBO Rep. 2019-08-29 [PMID: 31468690]
Merz T, Wepler M, Nusbaum B et al. Cystathionine-gamma -lyase expression is associated with mitochondrial respiration during sepsis-induced acute kidney injury in swine with atherosclerosis. Intensive Care Med Exp. 2018-10-20 [PMID: 30343340]
Seale LA, Ha HY, Hashimoto AC et al. Relationship between selenoprotein P and selenocysteine lyase: Insights into selenium metabolism. Free Radic Biol Med 2018-03-20 [PMID: 29567390]
Lee J, Sil Kang E, Kobayashi S et al. The viability of primary hepatocytes is maintained under a low cysteine-glutathione redox state with a marked elevation in ophthalmic acid production. Exp Cell Res 2017-10-26 [PMID: 29079265]
Kobayashi S, Lee J, Takao T, Fujii J et al. Increased ophthalmic acid production is supported by amino acid catabolism under fasting conditions in mice. Biochem Biophys Res Commun 2017-07-27 [PMID: 28757411]
Kurahashi T, Lee J, Nabeshima A et al. Ascorbic acid prevents acetaminophen-induced hepatotoxicity in mice by ameliorating glutathione recovery and autophagy. Arch Biochem Biophys 2016-08-15 [PMID: 27288086]
Ohmura M, Hishiki T, Yamamoto T et al. Impacts of CD44 knockdown in cancer cells on tumor and host metabolic systems revealed by quantitative imaging mass spectrometry. Nitric Oxide. 2014-01-01 [PMID: 25461272]
Bucci M, Papapetropoulos A, Vellecco V et al. cGMP-Dependent Protein Kinase Contributes to Hydrogen Sulfide-Stimulated Vasorelaxation. PLoS One. 2012-12-28 [PMID: 23285278]
Zhang L, Yang G, Untereiner A et al. Hydrogen sulfide impairs glucose utilization and increases gluconeogenesis in hepatocytes. Endocrinology. 2012-11-26 [PMID: 23183179]
Streeter E, Hart J, Badoer E. An investigation of the mechanisms of hydrogen sulfide-induced vasorelaxation in rat middle cerebral arteries. Naunyn Schmiedebergs Arch Pharmacol. 2012-07-17 [PMID: 22801977]
Guo H, Gai JW, Wang Y et al. Characterization of Hydrogen Sulfide and Its Synthases, Cystathionine b-Synthase and Cystathionine gamma-Lyase, in Human Prostatic Tissue and Cells. Urology. 2012-02-01 [PMID: 22310774]
Pei Y, Wu B, Cao Q et al. Hydrogen sulfide mediates the anti-survival effect of sulforaphane on human prostate cancer cells. Toxicology and Applied Pharmacology. 2011-10-08 [PMID: 22005276]
Zhu XY, Liu SJ, Liu YJ et al. Glucocorticoids suppress cystathionine gamma-lyase expression and H2S production in lipopolysaccharide-treated macrophages. Cell Mol Life Sci;67(7):1119-32. 2010-04-01 [PMID: 20063035]
Siebert N, Cantre D, Eipel C, Vollmar B. H2S contributes to the hepatic arterial buffer response and mediates vasorelaxation of the hepatic artery via activation of KATP channels. Am J Physiol Gastrointest Liver Physiol. 2008-10-30 [PMID: 18974309]
Halbert D, Domenyuk V, Spetzler D et al. Aptamers and uses thereof United States Patent Application US 9958448 B2 2018-01-01
Show All 15 Publications. Collapse Publications.

Cystathionase Antibody (S51)

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Gene Symbol	CTH
Entrez	1491(Human)
OMIM	219500(Human)
Uniprot	AAH15807(Human)