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Cyr61/CCN1 Antibody (3A7.1B8) - Azide and BSA Free

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Western Blot: Cyr61/CCN1 Antibody (3A7.1B8) - Azide and BSA Free [NBP2-80685] - WB analysis of (A) 12kDa Partial Recombinant Cyr61/CCN1 protein and (B) Human Liver lysate using Cyr61/CCN1 antibody (clone 3A7.1B8) at ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
3A7.1B8
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
1 mg/ml

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Cyr61/CCN1 Antibody (3A7.1B8) - Azide and BSA Free Summary

Immunogen
Partial recombinant protein from human Cyr61/CCN1 protein (between residues 100-300). [Swiss-Prot O00622]
Localization
Secreted (Cytoplasmic/Extracellular)
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CCN1
Purity
Protein G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 4 ug/ml
Application Notes
Protein CYR61 is a secreted protein and its expected immunolocalization would be cytoplasmic as well as the extracellular spaces.

Reactivity Notes

Immunogen's sequence similarity with other species: Rat (81%), Mouse (79%), Camel (88%), Naked Mole Rat (87%), Porcine (80%), Bovine / Sheep / Horse (82%), Chicken (63%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Concentration
1 mg/ml
Purity
Protein G purified

Alternate Names for Cyr61/CCN1 Antibody (3A7.1B8) - Azide and BSA Free

  • CCN family member 1
  • CCN1
  • CCN1IGF-binding protein 10
  • Cyr61
  • Cysteine-rich angiogenic inducer 61
  • cysteine-rich, angiogenic inducer, 61
  • GIG1
  • GIG1cysteine-rich heparin-binding protein 61
  • IBP-10
  • IGFBP-10
  • IGFBP10cysteine-rich, anigogenic inducer, 61
  • Insulin-like growth factor-binding protein 10
  • protein CYR61
  • Protein GIG1

Background

Cysteine-rich angiogenic inducer 61, also known as CYR61, is a growth factor-inducible, immediate-early gene that has multifaceted activities in various cancers. CYR61 is a secreted heparin-binding extracellular matrix-associated protein whose activities include the promotion of adhesion and chemotaxis, and the stimulation of fibroblast and endothelial cell growth. CYR61 induces angiogenesis and promotes tumor growth and is expressed in dermal fibroblasts during cutaneous wound healing.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CCN1