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Cyr61/CCN1 Antibody (3A7.1B8) [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
3A7.1B8
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-36490AF350
Alexa Fluor 405
NBP2-36490AF405
Alexa Fluor 488
NBP2-36490AF488
Alexa Fluor 532
NBP2-36490AF532
Alexa Fluor 594
NBP2-36490AF594
Alexa Fluor 647
NBP2-36490AF647
Alexa Fluor 700
NBP2-36490AF700
Alexa Fluor 750
NBP2-36490AF750
Biotin
NBP2-36490B
DyLight 350
NBP2-36490UV
DyLight 405
NBP2-36490V
DyLight 488
NBP2-36490G
DyLight 550
NBP2-36490R
DyLight 594
NBP2-36490DL594
DyLight 650
NBP2-36490C
DyLight 680
NBP2-36490FR
DyLight 755
NBP2-36490IR
FITC
NBP2-36490F
HRP
NBP2-36490H
Janelia Fluor 525
NBP2-36490JF525
Janelia Fluor 549
NBP2-36490JF549
Janelia Fluor 646
NBP2-36490JF646
Janelia Fluor 669
NBP2-36490JF669
Unconjugated
NBP2-36490
mFluor Violet 450 SE
NBP2-36490MFV450
mFluor Violet 500 SE
NBP2-36490MFV500
mFluor Violet 610 SE
NBP2-36490MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-36490
BSA Free
NBP2-36490SS
BSA Free
NBP2-36490
Azide and BSA Free
NBP2-80685
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Cyr61/CCN1 Antibody (3A7.1B8) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
Partial recombinant protein from human Cyr61/CCN1 protein (between residues 100-300). [Swiss-Prot O00622]
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CCN1
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Immunogen's sequence similarity with other species: Rat (81%), Mouse (79%), Camel (88%), Naked Mole Rat (87%), Porcine (80%), Bovine / Sheep / Horse (82%), Chicken (63%)

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for Cyr61/CCN1 Antibody (3A7.1B8) [CoraFluor™ 1]

  • CCN family member 1
  • CCN1
  • CCN1IGF-binding protein 10
  • Cyr61
  • Cysteine-rich angiogenic inducer 61
  • cysteine-rich, angiogenic inducer, 61
  • GIG1
  • GIG1cysteine-rich heparin-binding protein 61
  • IBP-10
  • IGFBP-10
  • IGFBP10cysteine-rich, anigogenic inducer, 61
  • Insulin-like growth factor-binding protein 10
  • protein CYR61
  • Protein GIG1

Background

CYR61 (Cysteine-rich angiogenic inducer 61) is a 381 amino acid secreted protein. It promotes cell proliferation, chemotaxis, angiogenesis extracellular matrix formation and cell adhesion and this appears to make CYR61 play a role in wound healing in skin fibroblasts. CYR61 expression is induced by growth factors. It interacts with several integrins and with heparan sulfate proteoglycan. CYR61 may play a role in T-cell non-Hodgkin's disease, breast cancer, epithelial neoplasia, hepatocellular carcinoma, ischemia, gastric cancer, endometriosis, prostate carcinoma, prostatitis, prostate cancer, breast carcinoma, cardiomyopathy, melanoma and adenocarcinoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CCN1