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CRHBP Antibody [Biotin]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Goat
Conjugate
Biotin
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Unconjugated
AF3087
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
AF3087
Carrier Free
AF3087
Carrier Free
AF3087-SP
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CRHBP Antibody [Biotin] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse CRHBP
Tyr25-Leu322
Accession # Q60571
Specificity
Detects mouse CRHBP in Western blots. In Western blots, approximately 70% cross-reactivity with recombinant human CRHBP is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
CRHBP
Purity Statement
Antigen Affinity-purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 0.1 ug/mL
Readout System

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CRHBP Antibody [Biotin]

  • corticotropin releasing hormone binding protein
  • corticotropin-releasing factor-binding protein
  • Corticotropin-releasing hormone-binding protein
  • CRFBP
  • CRFBPcorticotropin releasing hormone-binding protein
  • CRF-BPCRF-binding protein
  • CRHBP
  • CRH-BP

Background

Mouse CRHBP is a 37 kDa, monomeric CRH-binding glycoprotein that is secreted by cells of the rodent adrenal, medulla, cortical neurons and astrocytes, and prolactin positive cells of the pituitary. The mature molecule is 298 amino acids (aa) in length and contains six intrachain disulfide bonds. It binds CRH and CRH-like peptides, either serving as an antagonist for CRH binding to CRH receptor 1, or as a coreceptor for CRH binding to CRH receptor 2. Mature mouse CRHBP shares 94%, 87%, 85% and 80% aa sequence identity with rat, human, canine and bovine CRHBP, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CRHBP
Uniprot