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CNGB3 Antibody

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Immunohistochemistry-Paraffin: CNGB3 Antibody [NBP2-75087] - Negative Control showing staining of paraffin embedded Human Retina, with no primary antibody.
Immunohistochemistry-Paraffin: CNGB3 Antibody [NBP2-75087] - (2ug/ml) staining of paraffin embedded Human Retina. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining.

Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications ELISA, IHC
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

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CNGB3 Antibody Summary

Immunogen
Peptide with sequence C-ESDDKPTEHYYR, from the internal region of the protein sequence according to NP_061971.3.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
CNGB3
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 2-4 ug/ml
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin 2-4 ug/ml
  • Peptide ELISA 1:8000
Application Notes
Use in Immunohistochemistry-Frozen reported in scientific literature (PMID:35024589)..
Publications
Read Publication using
NBP2-75087 in the following applications:

Reactivity Notes

Use in Monkey reported in scientific literature (PMID:35024589) .

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
TBS (pH 7.3), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Antigen Affinity-purified

Alternate Names for CNGB3 Antibody

  • cyclic nucleotide gated channel beta 3

Background

Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficiency of the channel when coexpressed with CNGA3 . Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CNGB3 Antibody (NBP2-75087)(1)

We have publications tested in 1 confirmed species: Monkey.

We have publications tested in 1 application: IHC-Fr.


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IHC-Fr
(1)
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Secondary Antibodies

 

Isotype Controls

Additional CNGB3 Products

Array NBP2-75087

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Bioinformatics

Gene Symbol CNGB3