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Recombinant Human CLEC4E His Protein

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SDS-Page: Recombinant Human CLEC4E Protein [NBP2-52028]
SDS-Page: Recombinant Human CLEC4E Protein [NBP2-52028]

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.25 mg/ml

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Recombinant Human CLEC4E His Protein Summary

Description
A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 41-219 of Human CLEC4E

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MRCVVTFRIF QTCDEKKFQL PENFTELSCY NYGSGSVKNC CPLNWEYFQS SCYFFSTDTI SWALSLKNCS AMGAHLVVIN SQEEQEFLSY KKPKMREFFI GLSDQVVEGQ WQWVDGTPLT KSLSFWDVGE PNNIATLEDC ATMRDSSNPR QNWNDVTCFL NYFRICEMVG INPLNKGKSL
Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
CLEC4E
Purity
>85%, by SDS-PAGE

Applications/Dilutions

Dilutions
  • SDS-Page
Application Notes
Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.
Theoretical MW
22.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20 mM Tris-HCl buffer (pH 8.0), 10% glycerol
Preservative
No Preservative
Concentration
0.25 mg/ml
Purity
>85%, by SDS-PAGE

Alternate Names for Recombinant Human CLEC4E His Protein

  • CLEC4E
  • CLECSF9
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 9
  • C-type lectin domain family 4 member E
  • C-type lectin domain family 4, member E
  • Macrophage-inducible C-type lectin
  • MINCLE
  • MINCLEC-type lectin superfamily member 9

Background

CLEC4E encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein is a downstream target of CCAAT/enhancer binding protein (C/EBP), beta (CEBPB) and may play a role in inflammation. Alternative splice variants have been described but their full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol CLEC4E