CEACAM7 Antibody (962720) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Carcinoembryonic antigen-related cell adhesion molecule 7 (CEACAM-7), also known as CGM2, is an approximately 40 kDa GPI-anchored glycoprotein in the CEACAM family of adhesion molecules (1). Mature human CEACAM-7 consists of two Ig-like domains followed by the GPI anchor (2). Alternative splicing generates a short isoform that lacks the second Ig-like domain. CEACAM-7 is preferentially expressed on the luminal surface of epithelial cells near the mouth of colonic crypts and on pancreatic ductal epithelial cells (3, 4). It is down-regulated during colorectal adenoma progression (2-6) but can be up-regulated during the development of gastric carcinoma (7). R&D Systems in-house testing indicates that CEACAM-7 binds to CEACAM-1, consistent with the heterophilic interaction of CEACAM-1 with other CEACAM family members (1, 8, 9).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC.

Showing Publication 1 - 1 of 1.

Publication using MAB44782	Applications	Species
A Dhasmana, S Dhasmana, S Kotnala, P Laskar, S Khan, S Haque, M Jaggi, MM Yallapu, SC Chauhan CEACAM7 expression contributes to early events of pancreatic cancer Journal of advanced research, 2023-02-23;0(0):. 2023-02-23 [PMID: 36828119] (IHC, Human)	IHC	Human

Array MAB44782

• CEACAM7 Antibodies
• CEACAM7 ELISA Kits
• CEACAM7 Lysate
• CEACAM7 Proteins
• CEACAM7 Proteins and Enzyme