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CD30/TNFRSF8 Antibody (Hu8) [PE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
Hu8
Clonality
Monoclonal
Host
Human
Conjugate
PE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB9576U-100UG
Alexa Fluor 405
FAB9576V-100UG
Alexa Fluor 488
FAB9576G-100UG
Alexa Fluor 532
FAB9576X
Alexa Fluor 594
FAB9576T-100UG
Alexa Fluor 647
FAB9576R-100UG
Alexa Fluor 700
FAB9576N-100UG
Alexa Fluor 750
FAB9576S-100UG
Allophycocyanin
FAB9576A
Allophycocyanin/Cy7
FAB9576APCCY7
CoraFluor 1
FAB9576CL1
DyLight 350
FAB9576D
DyLight 405
FAB9576E
DyLight 488
FAB9576K
DyLight 550
FAB9576L
DyLight 594
FAB9576M
DyLight 650
FAB9576W
DyLight 680
FAB9576Y
DyLight 755
FAB9576Z
FITC
FAB9576F
HRP
FAB9576H
Janelia Fluor 525
FAB9576JF525
Janelia Fluor 549
FAB9576I
Janelia Fluor 646
FAB9576J
Janelia Fluor 669
FAB9576JF669
PE/Atto594
FAB9576PEATT594
PE/Cy5.5
FAB9576PECY55
PE/Cy7
FAB9576PECY7
PerCP
FAB9576C
Unconjugated
MAB9576-100
mFluor Violet 450 SE
FAB9576MFV450
mFluor Violet 500 SE
FAB9576MFV500
mFluor Violet 610 SE
FAB9576MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB9576-100
Carrier Free
MAB9576-100
Carrier Free
MAB9576-SP
Carrier Free
FAB9576S-100UG
Carrier Free
FAB9576R-100UG
Carrier Free
FAB9576N-100UG
Carrier Free
FAB9576G-100UG
Carrier Free
FAB9576V-100UG
Carrier Free
FAB9576U-100UG
Carrier Free
FAB9576T-100UG
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CD30/TNFRSF8 Antibody (Hu8) [PE] Summary

Immunogen
Human CD30/TNFRSF8
Specificity
Detects human CD30/TNFRSF8 in direct ELISAs. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Brentuximab. This product is for research use only.
Isotype
IgG1
Clonality
Monoclonal
Host
Human
Purity
Protein A or G purified from cell culture supernatant
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from cell culture supernatant

Alternate Names for CD30/TNFRSF8 Antibody (Hu8) [PE]

  • CD30 antigen
  • CD30
  • CD30KI-1
  • CD30L receptor
  • cytokine receptor CD30
  • D1S166EKi-1
  • Ki-1 antigen
  • Lymphocyte activation antigen CD30
  • TNFRSF8
  • tumor necrosis factor receptor superfamily member 8
  • tumor necrosis factor receptor superfamily, member 8

Background

CD30 is a type I transmembrane protein and a member of the tumor necrosis factor receptor superfamily of proteins. (1,2) Murine CD30 is expressed predominantly in the thymus, and it is inducible in mouse splenocytes stimulated with pokeweed mitogen or concanavalin A. (1) In anti-CD3epsilon-activated spleen cells, CD30 is expressed primarily on the surface of CD8+ T cells with peak expression on days 4 and 5. Stimulation of CD30+ CTL lines with plate-bound anti-CD30 directly signals IL-5 but not IFN; production. (1) While these studies demonstrate that CD30 directs cytokine secretion and suggest that CD30 may play a pivotal role in the pattern of cytokine production by T cells, the precise roles of CD30 and its ligand (CD153) in T-cell development have not been clearly defined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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