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CD27 Ligand/TNFSF7/CD70 Antibody (TAN 1-7) [DyLight 488]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA, Flow, Func, ICC/IF, CyTOF-ready
Clone
TAN 1-7
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-50150AF350
Alexa Fluor 405
NBP2-50150AF405
Alexa Fluor 488
NBP2-50150AF488
Alexa Fluor 532
NBP2-50150AF532
Alexa Fluor 594
NBP2-50150AF594
Alexa Fluor 647
NBP2-50150AF647
Alexa Fluor 700
NBP2-50150AF700
Alexa Fluor 750
NBP2-50150AF750
Allophycocyanin
NBP2-50150APC
Allophycocyanin/Cy7
NBP2-50150APCCY7
Biotin
NBP2-50150B
CoraFluor 1
NBP2-50150CL1
DyLight 350
NBP2-50150UV
DyLight 405
NBP2-50150V
DyLight 550
NBP2-50150R
DyLight 594
NBP2-50150DL594
DyLight 650
NBP2-50150C
DyLight 680
NBP2-50150FR
DyLight 755
NBP2-50150IR
FITC
NBP2-50150F
HRP
NBP2-50150H
Janelia Fluor 525
NBP2-50150JF525
Janelia Fluor 549
NBP2-50150JF549
Janelia Fluor 646
NBP2-50150JF646
Janelia Fluor 669
NBP2-50150JF669
PE
NBP2-50150PE
PE/Atto594
NBP2-50150PEATT594
PE/Cy5.5
NBP2-50150PECY55
PE/Cy7
NBP2-50150PECY7
PerCP
NBP2-50150PCP
Unconjugated
NBP2-50150
mFluor Violet 450 SE
NBP2-50150MFV450
mFluor Violet 500 SE
NBP2-50150MFV500
mFluor Violet 610 SE
NBP2-50150MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-50150
BSA Free
NBP2-50150
BSA Free
NBP2-50150-0.025ml
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CD27 Ligand/TNFSF7/CD70 Antibody (TAN 1-7) [DyLight 488] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
Recombinant mouse CD27 Ligand/TNFSF7/CD70 (extracellular domain, aa residues 41-195)
Specificity
This antibody is a non-depleting mAb that blocks the CD70-CD27 interaction.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
CD70
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • ELISA
  • Flow Cytometry
  • Functional
  • Immunocytochemistry/ Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CD27 Ligand/TNFSF7/CD70 Antibody (TAN 1-7) [DyLight 488]

  • CD27 Ligand
  • CD27-L
  • CD27LCD27 ligand
  • CD27LG
  • CD70 molecule
  • CD70
  • Ki-24 antigen
  • surface antigen CD70
  • TNFSF7
  • TNFSF7CD70 antigen
  • tumor necrosis factor (ligand) superfamily, member 7
  • Tumor necrosis factor ligand superfamily member 7

Background

CD70 is a type II transmembrane protein. It is a member of the TNF superfamily, expressed on activated B cells, activated dendritic cells, and some activated T cells (low levels). CD70 interacts with CD27 to promote T-B cell cross-stimulation and co-stimulate B cell proliferation and immunoglobulin production. Cells expressing CD70 can co-stimulate T cell proliferation and enhance the production of cytokines. The FR70 antibody blocks CD70 binding to CD27.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CD27 Ligand/TNFSF7/CD70 Antibody (NBP2-50150G) (0)

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CD70