Home » CD27 Ligand/TNFSF7/CD70 » CD27 Ligand/TNFSF7/CD70 Antibodies » CD27 Ligand/TNFSF7/CD70 Antibody (301731) [Unconjugated]
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CD27 Ligand/TNFSF7/CD70 Antibody (301731) [Unconjugated]

 (10 Publications)
 (1 Review)
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HEK293 human embryonic kidney cell line transfected with human CD27 Ligand/TNFSF7 (filled histogram) or irrelevant protein (open histogram) was stained with Mouse Anti-Human CD27 Ligand/TNFSF7 Monoclonal Antibody (Catalog # MAB2738) followed by Goat anti-mouse PE-conjugated secondary antibody (F0102B). Staining was performed using our Staining Membrane-associated Proteins protocol.
HEK293 human embryonic kidney cell line transfected with human CD27 Ligand/TNFSF7 (filled histogram) or irrelevant protein (open histogram) was stained with Mouse Anti-Human CD27 Ligand/TNFSF7 Monoclonal Antibody ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
301731
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB2738U-100UG
Alexa Fluor 405
FAB2738V-100UG
Alexa Fluor 488
FAB2738G-100UG
Alexa Fluor 532
FAB2738X
Alexa Fluor 594
FAB2738T-100UG
Alexa Fluor 647
FAB2738R-100UG
Alexa Fluor 700
FAB2738N-100UG
Alexa Fluor 750
FAB2738S-100UG
Allophycocyanin
FAB2738A
Allophycocyanin/Cy7
FAB2738APCCY7
Biotin
FAB2738B
CoraFluor 1
FAB2738CL1
DyLight 350
FAB2738D
DyLight 405
FAB2738E
DyLight 488
FAB2738K
DyLight 550
FAB2738L
DyLight 594
FAB2738M
DyLight 650
FAB2738W
DyLight 680
FAB2738Y
DyLight 755
FAB2738Z
FITC
FAB2738F
HRP
FAB2738H
Janelia Fluor 525
FAB2738JF525
Janelia Fluor 549
FAB2738I
Janelia Fluor 646
FAB2738J
Janelia Fluor 669
FAB2738JF669
PE
FAB2738P
PE/Atto594
FAB2738PEATT594
PE/Cy5.5
FAB2738PECY55
PE/Cy7
FAB2738PECY7
PerCP
FAB2738C
mFluor Violet 450 SE
FAB2738MFV450
mFluor Violet 500 SE
FAB2738MFV500
mFluor Violet 610 SE
FAB2738MFV610
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB2738-SP
Carrier Free
FAB2738T-100UG
Carrier Free
FAB2738R-100UG
Carrier Free
FAB2738N-100UG
Carrier Free
FAB2738G-100UG
Carrier Free
FAB2738V-100UG
Carrier Free
FAB2738S-100UG
Carrier Free
FAB2738U-100UG
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CD27 Ligand/TNFSF7/CD70 Antibody (301731) [Unconjugated] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human CD27 Ligand/TNFSF7
Gln45-Pro193
Accession # AAA36175
Specificity
Detects human CD27 Ligand/TNFSF7 in direct ELISAs.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
CD70
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25 ug/10^6 cells
Reviewed Applications
Read 1 Review rated 4
using
MAB2738 in the following application:
Publications
Read Publications using
MAB2738 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CD27 Ligand/TNFSF7/CD70 Antibody (301731) [Unconjugated]

  • CD27 Ligand
  • CD27-L
  • CD27LCD27 ligand
  • CD27LG
  • CD70 molecule
  • CD70
  • Ki-24 antigen
  • surface antigen CD70
  • TNFSF7
  • TNFSF7CD70 antigen
  • tumor necrosis factor (ligand) superfamily, member 7
  • Tumor necrosis factor ligand superfamily member 7

Background

CD27 Ligand is a member of the tumor necrosis factor superfamily (TNFSF7) and is also designated CD70. CD27 Ligand is a type II transmembrane protein expressed by activated T and B cells. It binds to CD27 on mature T cells and a subset of thymocytes. CD27 Ligand induces the proliferation of costimulated T cells and enhances the generation of cytolytic T cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CD27 Ligand/TNFSF7/CD70 Antibody (MAB2738)(10)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 3 applications: IHC, IHC-P, Immunohistochemistry.


Filter By Application
IHC
(2)
IHC-P
(1)
Immunohistochemistry
(2)
All Applications
Filter By Species
Human
(5)
Mouse
(1)
All Species
Showing Publications 1 - 10 of 10.
Publications using MAB2738 Applications Species
Acharya, S;Basar, R;Daher, M;Rafei, H;Li, P;Uprety, N;Ensley, E;Shanley, M;Kumar, B;Banerjee, PP;Melo Garcia, L;Lin, P;Mohanty, V;Kim, KH;Jiang, X;Pan, Y;Li, Y;Liu, B;Nunez Cortes, AK;Zhang, C;Fathi, M;Rezvan, A;Montalvo, MJ;Cha, SL;Reyes-Silva, F;Shrestha, R;Guo, X;Kundu, K;Biederstadt, A;Muniz-Feliciano, L;Deyter, GM;Kaplan, M;Jiang, XR;Liu, E;Jain, A;Roszik, J;Fowlkes, NW;Solis Soto, LM;Raso, MG;Khoury, JD;Lin, P;Vega, F;Varadarajan, N;Chen, K;Marin, D;Shpall, EJ;Rezvani, K; CD28 costimulation augments CAR signaling in NK cells via the LCK/CD3Z/ZAP70 signaling axis Cancer discovery 2024-06-20 [PMID: 38900051] (Immunohistochemistry, Human) Immunohistochemistry Human
Van den Eynde, A;Gehrcken, L;Verhezen, T;Lau, HW;Hermans, C;Lambrechts, H;Flieswasser, T;Quatannens, D;Roex, G;Zwaenepoel, K;Marcq, E;Joye, P;Cardenas De La Hoz, E;Deben, C;Gasparini, A;Montay-Gruel, P;Le Compte, M;Lion, E;Lardon, F;Van Laere, S;Siozopoulou, V;Campillo-Davo, D;De Waele, J;Pauwels, P;Jacobs, J;Smits, E;Van Audenaerde, JRM; IL-15-secreting CAR natural killer cells directed toward the pan-cancer target CD70 eliminate both cancer cells and cancer-associated fibroblasts Journal of hematology & oncology 2024-02-09 [PMID: 38331849] (Immunohistochemistry, Human) Immunohistochemistry Human
Huang, RR;Chen, Z;Kroeger, N;Pantuck, A;Said, J;Kluger, HM;Shuch, B;Ye, H; CD70 is Consistently Expressed in Primary and Metastatic Clear Cell Renal Cell Carcinoma Clinical genitourinary cancer 2023-12-13 [PMID: 38195301] (Human) Human
Man Nie, Weicheng Ren, Xiaofei Ye, Mattias Berglund, Xianhuo Wang, Karin Fjordén et al. The dual role of CD70 in B‐cell lymphomagenesis Clinical and Translational Medicine 12/5/2022 [PMID: 36471481]
David S. Tourigny, Mark Zucker, Minsoo Kim, Paul Russo, Jonathan Coleman, Chung-Han Lee et al. Molecular Characterization of the Tumor Microenvironment in Renal Medullary Carcinoma Frontiers in Oncology 6/28/2022 [PMID: 35837094]
Mayu Shiomi, Shinya Matsuzaki, Satoshi Serada, Koji Matsuo, Chihiro Mizuta‐Odani, Mariko Jitsumori et al. CD70 antibody‐drug conjugate: A potential novel therapeutic agent for ovarian cancer Cancer Science 9/1/2021 [PMID: 34117815]
R Nakae, S Matsuzaki, S Serada, K Matsuo, M Shiomi, K Sato, Y Nagase, S Matsuzaki, S Nakagawa, K Hiramatsu, A Okazawa, T Kimura, T Egawa-Taka, E Kobayashi, Y Ueda, K Yoshino, T Naka, T Kimura CD70 antibody-drug conjugate as a potential therapeutic agent for uterine leiomyosarcoma Am. J. Obstet. Gynecol., 2020-08-19;0(0):. 2020-08-19 [PMID: 32822640] (IHC, Human) IHC Human
T Flieswasse, V Camara-Cla, A Danu, J Bosq, V Ribrag, P Zabrocki, L Van Rompae, H de Haard, K Zwaenepoel, E Smits, P Pauwels, J Jacobs Screening a Broad Range of Solid and Haematological Tumour Types for CD70 Expression Using a Uniform IHC Methodology as Potential Patient Stratification Method Cancers (Basel), 2019-10-22;11(10):. 2019-10-22 [PMID: 31652572] (IHC-P, Human) IHC-P Human
Miikkulainen P, Hogel H, Rantanen K et al. HIF prolyl hydroxylase PHD3 regulates translational machinery and glucose metabolism in clear cell renal cell carcinoma Cancer Metab 7/6/2017 [PMID: 28680592]
UB Hagemann, D Mihaylova, SR Uran, J Borrebaek, D Grant, RM Bjerke, J Karlsson, AS Cuthbertso Targeted alpha therapy using a novel CD70 targeted thorium-227 conjugate in in vitro and in vivo models of renal cell carcinoma Oncotarget, 2017-01-01;0(0):. 2017-01-01 [PMID: 28446716] (IHC, Mouse) IHC Mouse

Review for CD27 Ligand/TNFSF7/CD70 Antibody (MAB2738) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using MAB2738:
Filter by Applications
IHC-P
(1)
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Filter by Species
Human
(1)
All Species
Images Ratings Applications Species Date Details
Immunohistochemistry-Paraffin CD27 Ligand/TNFSF7/CD70 MAB2738
Enlarge 		4
reviewed by:
Verified Customer
 IHC-P Human 01/16/2020
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Summary

ApplicationImmunohistochemistry-Paraffin
Sample TestedNK/T cell lymphoma
SpeciesHuman
LotWVG0218121

Comments

CommentspH 9 antigen retrieval

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FAQs for CD27 Ligand/TNFSF7/CD70 Antibody (MAB2738) (0)

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Secondary Antibodies

 

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Immunohistochemistry-Paraffin CD27 Ligand/TNFSF7/CD70 MAB2738
Enlarge
 Verified Customer
01/16/2020
Application: IHC-P
Species: Human
read this review

Bioinformatics

Gene Symbol CD70
Uniprot