CD229/SLAMF3/Lymphocyte Antigen 9 Antibody - BSA Free Summary
Immunogen |
Antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SLAMF3. The immunogen is located within amino acids 520 - 570 of SLAMF3. Amino Acid Squence: QPTPTSDSSSDSNLTTEED |
Specificity |
At least three isoforms of SLAMF3 are known to exist. SLAMF3 antibody is predicted to not cross-react with other SLAM protein family members. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
LY9 |
Purity |
Peptide affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA 1:100-1:2000
- Immunocytochemistry/ Immunofluorescence 10-20 ug/ml
- Western Blot 1-2 ug/ml
|
Control Peptide |
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Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
PBS |
Preservative |
0.02% Sodium Azide |
Concentration |
1 mg/ml |
Purity |
Peptide affinity purified |
Alternate Names for CD229/SLAMF3/Lymphocyte Antigen 9 Antibody - BSA Free
Background
The signaling lymphocyte-activation molecule family member 3 (SLAMF3), also known as LY9, is a cell surface receptor that is expressed on T and B lymphocytes and belongs to the CD150/SLAMF1 receptor family. SLAMF3 was identified through a yeast two-hybrid screening in which SLAMF3 bound to the X-linked lymphoproliferative disease gene product SAP, suggesting that in activated T cells, SLAMF3 signaling can be triggered SAP. Its expression on the cell surface appears to be regulated via its interaction with the clathrin-associated adaptor complex 2 (AP-2). Despite its similarity to SLAMF1 in structure and interactions with SAP, SLAMF3-deficient mice do not exhibit phenotypic characteristics associated with SLAMF1- and SAP-deficient mice, suggesting that SLAMF3 plays other roles in T cell activation.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for CD229/SLAMF3/Lymphocyte Antigen 9 Antibody (NBP1-76557) (0)
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Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
Video Protocols
FAQs for CD229/SLAMF3/Lymphocyte Antigen 9 Antibody (NBP1-76557). (Showing 1 - 1 of 1 FAQ).
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Could you tell more about its immunogen? Where exactly does this antibody binds to?
- The immunogen sequence is proprietary but I can indicate that it is from within aa501-550 of the protein sequence.
Secondary Antibodies
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Isotype Controls
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