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CCL24/Eotaxin-2/MPIF-2 Antibody [Biotin]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, ELISA(Det)
Clonality
Polyclonal
Host
Goat
Conjugate
Biotin
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Unconjugated
AF528
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
AF528
Carrier Free
AF528
Carrier Free
AF528-SP
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CCL24/Eotaxin-2/MPIF-2 Antibody [Biotin] Summary

Immunogen
E. coli-derived recombinant mouse CCL24/Eotaxin-2/MPIF-2 (R&D Systems, Catalog # 528-MP)
Ile24-Val119
Accession # Q9JKC0
Specificity
Detects mouse CCL24/Eotaxin-2/MPIF-2 in ELISAs and Western blots. In sandwich immunoassays, less than 0.05% cross-reactivity with recombinant human (rh) Eotaxin-2, rhEotaxin, recombinant mouse (rm) Eotaxin, rhEotaxin-3, rmMIP-1 alpha , rmMIP-1 beta , rmMARC, rmRANTES, rm6Ckine and rmTARC is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
CCL24
Purity Statement
Antigen Affinity-purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
  • ELISA Detection (Matched Antibody Pair) 0.1-0.4 ug/mL
  • ELISA Standard (Matched Pair)
  • Western Blot 0.1 ug/mL
Application Notes
ELISA Capture: Mouse CCL24/Eotaxin-2/MPIF-2 Antibody (Catalog # MAB528)
ELISA Detection: Mouse CCL24/Eotaxin-2/MPIF-2 Biotinylated Antibody (Catalog # BAF528)
Standard: Recombinant Mouse CCL24/Eotaxin-2/MPIF-2 aa 24-119 (Catalog # 528-MP)
Readout System
Publications
Read Publications using
BAF528 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CCL24/Eotaxin-2/MPIF-2 Antibody [Biotin]

  • CCL24
  • chemokine (C-C motif) ligand 24
  • Ckb-6
  • Eosinophil chemotactic protein 2
  • Eotaxin-2
  • member 24
  • MPIF2
  • MPIF-2
  • MPIF2Myeloid progenitor inhibitory factor 2
  • MPIF-2Small-inducible cytokine A24
  • SCYA24CK-beta-6

Background

Eotaxin-2, also named myeloid progenitor inhibitory factor (MPIF-2), is a member of the CC chemokine subfamily and is designated CCL24. Eotaxin-2 is constitutively expressed in the jejunum and spleen. It can also be induced in the lung by allergen challenge and IL-4. LPS and IL-4 also differentially regulate the expression of Eotaxin-2 in monocytes and macrophages. Mouse Eotaxin-2 cDNA encodes a 119 amino acid (aa) residue precursor protein that shares approximately 58% aa sequence identity with human Eotaxin-2. Functionally, Eotaxin-2 is most closely related to eotaxin/CCL11 and Eotaxin-3/CCL26. The three proteins share low sequence homology but have been shown to be potent eosinophil chemoattractants that bind and activate the chemokine receptor CCR3, a receptor that is highly expressed in eosinophils. Eotaxin-2 also has the ability to suppress myeloid cell proliferation, a biological function not shared by eotaxin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CCL24/Eotaxin-2/MPIF-2 Antibody (BAF528)(2)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: ELISA Development (Detection).


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ELISA Development (Detection)
(2)
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Bioinformatics

Gene Symbol CCL24
Uniprot