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CCL17/TARC Antibody (54015)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, CyTOF-ready, Flow
Clone
54015
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC3641U-100UG
Alexa Fluor 405
IC3641V-100UG
Alexa Fluor 488
IC3641G-100UG
Alexa Fluor 532
FAB3641X
Alexa Fluor 594
IC3641T-100UG
Alexa Fluor 647
IC3641R-100UG
Alexa Fluor 700
IC3641N-100UG
Alexa Fluor 750
IC3641S-100UG
Allophycocyanin
FAB3641A
Biotin
FAB3641B
DyLight 350
FAB3641D
DyLight 405
FAB3641E
DyLight 488
FAB3641K
DyLight 550
FAB3641L
DyLight 594
FAB3641M
DyLight 650
FAB3641W
DyLight 680
FAB3641Y
DyLight 755
FAB3641Z
FITC
FAB3641F
HRP
FAB3641H
Janelia Fluor 525
FAB3641JF525
Janelia Fluor 549
FAB3641I
Janelia Fluor 585
FAB3641JF585
Janelia Fluor 635
FAB3641JF635
Janelia Fluor 646
FAB3641J
Janelia Fluor 669
FAB3641JF669
PerCP
FAB3641C
Phycoerythrin
IC3641P
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
IC3641P
Carrier Free
MAB3641-SP
Carrier Free
IC3641T-100UG
Carrier Free
IC3641S-100UG
Carrier Free
IC3641R-100UG
Carrier Free
IC3641N-100UG
Carrier Free
IC3641G-100UG
Carrier Free
IC3641V-100UG
Carrier Free
IC3641U-100UG
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CCL17/TARC Antibody (54015) Summary

Immunogen
E. coli-derived recombinant human CCL17/TARC
Ala24-Ser94
Accession # Q92583.1
Specificity
Detects human CCL17/TARC in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human CCL1, 2, 3, 4, 5, 7, 8, 11, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, recombinant mouse CCL1, 2, 3, 4, 5, 6, 7, 8, 9, 11, 12, 17, 19, 20, 21, 22, 24, 25, 27 or recombinant rat CCL20 is observed.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CCL17
Purity Statement
Protein A or G purified from ascites
Innovator's Reward
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Intracellular Staining by Flow Cytometry 2.5 ug/10^6 cells
  • Western Blot 1 ug/mL
Publications
Read Publication using
MAB3641 in the following applications:

  • ICC
    1 publication

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CCL17/TARC Antibody (54015)

  • ABCD-2
  • CC chemokine TARC
  • C-C motif chemokine 17
  • CCL17
  • chemokine (C-C motif) ligand 17
  • MGC138273
  • SCYA17
  • SCYA17MGC138271
  • small inducible cytokine subfamily A (Cys-Cys), member 17
  • Small-inducible cytokine A17
  • T cell-directed CC chemokine
  • TARC
  • TARCA-152E5.3
  • Thymus and activation-regulated chemokine

Background

CCL17, also called TARC, is a member of the CC chemokine family. CCL17 cDNA encodes a highly basic 94 amino acid (aa) residue precursor protein with a 23 aa residue signal peptide that is cleaved to generate the 71 aa residue mature secreted protein. Among CC chemokine family members, CCL17 has approximately 24‑29% amino acid sequence identity with CCL1, 2, 3, 4, 5, 7 and 8. The gene for human CCL17 has been mapped to chromosome 16q13 rather than chromosome 17 where the genes for many human CC chemokines are clustered. CCL17 is constitutively expressed in thymus, and at a lower level in lung, colon, and small intestine. CCL17 is also transiently expressed in stimulated peripheral blood mononuclear cells. Recombinant CCL17 has been shown to be chemotactic for T cell lines but not monocytes or neutrophils. CCL17 was identified to be a specific functional ligand for CCR4, a receptor that is selectively expressed on T cells.

  1. Imai, T. et al. (1997) J. Biol. Chem. 272:15036.
  2. Imai, T. et al. (1996) J. Biol. Chem. 271:21514.
  3. Nomiyama, H. et al. (1997) Genomics 40:211.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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CCL17/TARC
Antibody (54015)
MAB3641
CCL17/TARC Antibody (54015)
Species: Hu
Applications: WB, CyTOF-ready, Flow

Publications for CCL17/TARC Antibody (MAB3641)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: ICC.


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(1)
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Bioinformatics

Gene Symbol CCL17
Uniprot