Home » Caveolin-3 » Caveolin-3 Antibodies » Caveolin-3 Antibody (682708)

Caveolin-3 Antibody (682708)

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Western blot shows lysates of human heart tissue, human skeletal muscle tissue, rat heart tissue, rat skeletal muscle tissue, and mouse heart tissue. PVDF Membrane was probed with 0.5 µg/mL of Mouse Anti-Human Caveolin-3 Monoclonal Antibody (Catalog # MAB6706) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for Caveolin-3 at approximately 20 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.
Western blot shows lysates of human heart tissue, human skeletal muscle tissue, rat heart tissue, rat skeletal muscle tissue, and mouse heart tissue. PVDF Membrane was probed with 0.5 µg/mL of Mouse Anti-Human ...read more
Caveolin-3 was detected in immersion fixed paraffin-embedded sections of human skeletal muscle using Mouse Anti-Human Caveolin-3 Monoclonal Antibody (Catalog # MAB6706) at 15 µg/mL overnight at 4 °C. Before incubation ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
682708
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Formulation Size Price
Carrier Free
MAB6706-SP
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Caveolin-3 Antibody (682708) Summary

Immunogen
E. coli-derived recombinant human Caveolin-3
Met1-Pro83
Accession # P56539
Specificity
Detects human Caveolin-3 in direct ELISAs.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
CAV3
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 8-25 ug/mL
  • Western Blot 0.5 ug/mL
Publications
Read Publication using
MAB6706 in the following applications:

  • IHC
    1 publication

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Sterile PBS to a final concentration of 0.5 mg/mL.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Caveolin-3 Antibody (682708)

  • CAV3
  • caveolin 3
  • Caveolin3
  • Caveolin-3
  • LGMD1C
  • LGMD1CMGC126100
  • LQT9
  • LQT9MGC126101
  • M-caveolin
  • MGC126129
  • VIP21
  • VIP-21

Background

Caveolin-3 is an 18 kDa member of the Caveolin family of proteins which are major protein components of plasma membrane caveolae. It is preferentially expressed in muscle cells where it regulates the localization and activity of potassium channels and the nicotinic acetylcholine receptor. Caveolin-3 mutations are associated with several skeletal muscle defects. It contains a central membrane-embedded sequence (aa 84-104) flanked by two cytoplasmic domains (aa 1-83 and 105-151). Over aa 1-83, human Caveolin-3 shares 94% aa identity with mouse and rat Caveolin-3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Caveolin-3 Antibody (MAB6706)(1)

We have publications tested in 1 confirmed species: Rat.

We have publications tested in 1 application: IHC.


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Bioinformatics

Gene Symbol CAV3
Uniprot