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Cardiac Troponin T Antibody (200805) [Unconjugated] - (Cardiac)

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Troponin T was detected in immersion fixed BG01V human embryonic stem cells differentiated into cardiomyocytes using Mouse Anti-Human Troponin T (Cardiac) Monoclonal Antibody (Catalog # MAB1874) at 10 µg/mL for 3 hours ...read more
Troponin T was detected in immersion fixed paraffin-embedded sections of human heart using Mouse Anti-Human Troponin T (Cardiac) Monoclonal Antibody (Catalog # MAB1874) at 15 µg/mL overnight at 4 °C. Tissue was ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, ICC/IF
Clone
200805
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

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Cardiac Troponin T Antibody (200805) [Unconjugated] - (Cardiac) Summary

Immunogen
Human cardiac Troponin T
Specificity
Detects purified human Troponin T (Cardiac) in direct ELISAs.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
TNNT2
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry 8-25 ug/mL
  • Immunohistochemistry 8-25 ug/mL
Publications
Read Publications using
MAB1874 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Cardiac Troponin T Antibody (200805) [Unconjugated] - (Cardiac)

  • Cardiac Muscle Troponin T
  • Cardiomyopathy, Dilated 1D (Autosomal Dominant)
  • Cardiomyopathy, Hypertrophic
  • CMD1D
  • CMH2
  • CMPD2
  • cTnT
  • LVNC6
  • RCM3
  • TNNT2
  • TnTC
  • troponin T type 2 (cardiac)
  • Troponin T
  • troponin T, cardiac muscle
  • Troponin T2, Cardiac Type
  • Truncated Cardiac Troponin T

Background

Troponin T is one of three troponin isoforms found in the tropomyosin-troponin complex. This complex is responsible for the calcium sensitivity of the contractile apparatus in the muscle. Cardiac Troponin T is used as a biological marker for cardiomyocytes and its level in serum is frequently used as an indicator of myocardial cell injury.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Cardiac Troponin T Antibody (MAB1874)(19)

We have publications tested in 3 confirmed species: Human, Mouse, Transgenic Mouse.

We have publications tested in 4 applications: Flow Cytometry, ICC, Immunocytochemistry, Immunohistochemistry.


Filter By Application
Flow Cytometry
(4)
ICC
(8)
Immunocytochemistry
(2)
Immunohistochemistry
(1)
All Applications
Filter By Species
Human
(9)
Mouse
(2)
Transgenic Mouse
(1)
All Species
Showing Publications 1 - 10 of 19. Show All 19 Publications.
Publications using MAB1874 Applications Species
Zhu, J;Liu, X;Liu, Z;Deng, Y;Xu, J;Liu, K;Zhang, R;Meng, X;Fei, P;Yu, T;Zhu, D; SOLID: minimizing tissue distortion for brain-wide profiling of diverse architectures Nature communications 2024-09-27 [PMID: 39333107] (Immunohistochemistry, Mouse) Immunohistochemistry Mouse
Wang, L;Chen, C;Zhou, H;Tao, L;Xu, E; Nicotinamide Riboside-Driven Modulation of SIRT3/mtROS/JNK Signaling Pathways Alleviates Myocardial Ischemia-Reperfusion Injury International journal of medical sciences 2024-08-12 [PMID: 39239543] (Immunocytochemistry, Mouse, Transgenic Mouse) Immunocytochemistry Mouse, Transgenic Mouse
Ye, C;Yang, C;Zhang, H;Gao, R;Liao, Y;Zhang, Y;Jie, L;Zhang, Y;Cheng, T;Wang, Y;Ren, J; Canonical Wnt signaling directs the generation of functional human PSC-derived atrioventricular canal cardiomyocytes in bioprinted cardiac tissues Cell stem cell 2024-02-10 [PMID: 38366588] (Flow Cytometry, Immunocytochemistry, Human) Flow Cytometry, Immunocytochemistry Human
Zachary T. Olmsted, Maria Belen Paredes-Espinosa, Janet L. Paluh Generation of human elongating multi-lineage organized cardiac gastruloids STAR Protocols 2022-12-16 [PMID: 36595961]
YH Chen, PS Huang, MH Wen, M Pan, DF Lee, TY Chen Generation of a homozygous knock-in human embryonic stem cell line expressing mEos4b-tagged CTR1 Oncogene, 2022-06-14;63(0):102845. 2022-06-14 [PMID: 35728441] (ICC, Human) ICC Human
Olmsted ZT, Paluh JL. A combined human gastruloid model of cardiogenesis and neurogenesis iScience 2022-06-17 [PMID: 35721464]
R Pivato, S Klimovic, D Kabanov, F Sverák, M Pesl, J Pribyl, V Rotrekl hESC derived cardiomyocyte biosensor to detect the different types of arrhythmogenic properties of drugs Oncogene, 2022-05-20;1216(0):339959. 2022-05-20 [PMID: 35691674] (ICC, Human) ICC Human
Emmi Helle, Minna Ampuja, Alexandra Dainis, Laura Antola, Elina Temmes, Erik Tolvanen et al. HiPS-Endothelial Cells Acquire Cardiac Endothelial Phenotype in Co-culture With hiPS-Cardiomyocytes Frontiers in Cell and Developmental Biology 2021-08-06 [PMID: 34422835]
PS Huang, MH Wen, X Xie, A Xu, DF Lee, TY Chen Generation of a homozygous knock-in human embryonic stem cell line expressing SNAP-tagged SOD1 Stem Cell Research, 2021-06-06;54(0):102415. 2021-06-06 [PMID: 34118566] (ICC, Human) ICC Human
J Jung, S Hwang, H Seol, AH Kim, HM Lee, JJ Sung, SM Jeong, YM Choi, JK Jun, DW Kim, J Jang Generation of Brachyury-mCherry knock-in reporter human pluripotent stem cell line (SNUe003-A-2) using CRISPR/CAS9 nuclease Stem Cell Research, 2021-04-10;53(0):102321. 2021-04-10 [PMID: 33878708] (Flow Cytometry, ICC, Human) Flow Cytometry, ICC Human
Show All 19 Publications.

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Bioinformatics

Gene Symbol TNNT2