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Carboxypeptidase E/CPE Antibody (420709)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clone
420709
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Formulation Size Price
Carrier Free
MAB3587-SP
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Carboxypeptidase E/CPE Antibody (420709) Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Carboxypeptidase E/CPE
Arg42-Ser453
Accession # P16870
Specificity
Detects human Carboxypeptidase E/CPE in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) CPA1, rhCPA2, rhCPB1, or recombinant mouse CPA4 is observed.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
CPE
Purity Statement
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • Immunoprecipitation 25 ug/mL
  • Western Blot 1 ug/mL
Publications
Read Publications using
MAB3587 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Carboxypeptidase E/CPE Antibody (420709)

  • Carboxypeptidase E
  • Carboxypeptidase H
  • CPE
  • CPH
  • CPH-1
  • EC 3.4.17
  • EC 3.4.17.10
  • Enkephalin convertase
  • Prohormone-processing carboxypeptidase

Background

Carboxypeptidase E (CPE) is a peripheral membrane protein that cleaves C-terminal amino acid residues and is involved in the processing of numerous peptide hormones and neurotransmitters. CPE knockout mice live but become obese due to impaired glucose clearance and insulin resistance. The CPE precursor includes a signal peptide (aa 1‑25), a propeptide (aa 26‑42) and a mature chain (aa 43‑476). The amino acid sequence of human CPE is 99.8%, 96.6%, 96.3%, and 90.2% identical to that of chimpanzee, mouse, dog and chicken.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Carboxypeptidase E/CPE Antibody (MAB3587)(4)

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 3 applications: IHC-P, Immunoprecipitation, Western Blot.


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IHC-P
(1)
Immunoprecipitation
(1)
Western Blot
(2)
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(2)
Mouse
(1)
Rat
(1)
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Bioinformatics

Gene Symbol CPE
Uniprot