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Calcineurin Antibody

Images

 
Western Blot: Calcineurin Antibody [NBP3-42331] - Sample: Mouse Cerebrum lysate; Primary Ab: 1ug/ml NBP3-42331; Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
Western Blot: Calcineurin Antibody [NBP3-42331] - Sample: Mouse Skeletal muscle lysate; Primary Ab: 1ug/ml NBP3-42331; Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
Immunohistochemistry-Paraffin: Calcineurin Antibody [NBP3-42331] - DAB staining on IHC-P; Samples: Human Liver Tissue; Primary Ab: 10ug/ml NBP3-42331; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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Calcineurin Antibody Summary

Immunogen
Immunogen sequence: Ile7-Ser301 (Uniprot#: Q08209)
Clonality
Polyclonal
Host
Rabbit
Gene
PPP3CA
Purity
Antigen and protein A Affinity-purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 5-20ug/mL
  • Immunohistochemistry 5-20ug/mL
  • Western Blot 0.5-2ug/mL

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.01M PBS, pH7.4, 50% glycerol
Preservative
0.05% Proclin 300
Concentration
0.5 mg/ml
Purity
Antigen and protein A Affinity-purified

Alternate Names for Calcineurin Antibody

  • calcineurin A alpha
  • calcineurin subunit B type 1
  • Calcineurin
  • CALN
  • CALNA
  • CALNB1
  • CCN1
  • CNA1
  • CNB1

Background

Enables several functions, including ATPase binding activity; calmodulin binding activity; and calmodulin-dependent protein phosphatase activity. Involved in several processes, including calcineurin-NFAT signaling cascade; peptidyl-serine dephosphorylation; and response to calcium ion. Located in several cellular components, including cytosol; dendritic spine; and nucleoplasm. Part of calcineurin complex. Colocalizes with cytoplasmic side of plasma membrane. Implicated in developmental and epileptic encephalopathy 91. Biomarker of focal segmental glomerulosclerosis and schizophrenia. [provided by Alliance of Genome Resources, Apr 2022]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Calcineurin Antibody (NBP3-42331) (0)

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Calcineurin Antibody (NBP3-42331) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for Calcineurin Antibody (NBP3-42331)

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Blogs on Calcineurin.

GAPDH: More than a housekeeping gene
GAPDH is a 146kD tetramer glycolytic pathway metabolic enzyme composed of four 30-40 kDa subunits. It is responsible for reversibly phosphorylating its substrate glyceraldehyde 3-phosphate within the glycolytic pathway.  Apart from its role in gl...  Read full blog post.

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Bioinformatics

Gene Symbol PPP3CA