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Calcineurin Antibody

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Product Details

Summary
Reactivity Hu, Mu, Rt, BvSpecies Glossary
Applications WB, IHC, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Calcineurin Antibody Summary

Immunogen
The immunogen used for the anti-Calcineurin was a purified peptide conjugated to KLH. The sequence of the peptide is NH2-Arg-Met-Pro-Pro-Arg-Arg-Asp-Ala-Met-Pro-Ser-Asp-Ala-COOH (a.a. 482-494) corresponding to a 60kDa protein
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PPP3CA
Purity
Ammonium sulfate precipitation
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Applications/Dilutions

Dilutions
  • Immunocytochemistry
  • Immunohistochemistry
  • Western Blot
Application Notes
.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Phosphate buffered saline
Preservative
0.08% Sodium Azide
Purity
Ammonium sulfate precipitation

Alternate Names for Calcineurin Antibody

  • calcineurin A alpha
  • calcineurin subunit B type 1
  • Calcineurin
  • CALN
  • CALNA
  • CALNB1
  • CCN1
  • CNA1
  • CNB1

Background

Enables several functions, including ATPase binding activity; calmodulin binding activity; and calmodulin-dependent protein phosphatase activity. Involved in several processes, including calcineurin-NFAT signaling cascade; peptidyl-serine dephosphorylation; and response to calcium ion. Located in several cellular components, including cytosol; dendritic spine; and nucleoplasm. Part of calcineurin complex. Colocalizes with cytoplasmic side of plasma membrane. Implicated in developmental and epileptic encephalopathy 91. Biomarker of focal segmental glomerulosclerosis and schizophrenia. [provided by Alliance of Genome Resources, Apr 2022]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional Calcineurin Products

Blogs on Calcineurin.

GAPDH: More than a housekeeping gene
GAPDH is a 146kD tetramer glycolytic pathway metabolic enzyme composed of four 30-40 kDa subunits. It is responsible for reversibly phosphorylating its substrate glyceraldehyde 3-phosphate within the glycolytic pathway.  Apart from its role in gl...  Read full blog post.

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Bioinformatics

Gene Symbol PPP3CA