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BubR1 Antibody [Janelia Fluor® 646]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 646

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-579AF350
Alexa Fluor 405
NB100-579AF405
Alexa Fluor 488
NB100-579AF488
Alexa Fluor 532
NB100-579AF532
Alexa Fluor 594
NB100-579AF594
Alexa Fluor 647
NB100-579AF647
Alexa Fluor 700
NB100-579AF700
Alexa Fluor 750
NB100-579AF750
Allophycocyanin
NB100-579APC
Biotin
NB100-579B
CoraFluor 1
NB100-579CL1
DyLight 350
NB100-579UV
DyLight 405
NB100-579V
DyLight 488
NB100-579G
DyLight 550
NB100-579R
DyLight 594
NB100-579DL594
DyLight 650
NB100-579C
DyLight 680
NB100-579FR
DyLight 755
NB100-579IR
FITC
NB100-579F
HRP
NB100-579H
Janelia Fluor 525
NB100-579JF525
Janelia Fluor 549
NB100-579JF549
Janelia Fluor 585
NB100-579JF585
Janelia Fluor 635
NB100-579JF635
Janelia Fluor 669
NB100-579JF669
PE
NB100-579PE
PerCP
NB100-579PCP
Unconjugated
NB100-579
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BubR1 Antibody [Janelia Fluor® 646] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residues 350 and 400 of human budding uninhibited by benzimidazoles 1 homolog beta using the numbering given in TrEMBL entry Q8WV50 (GeneID 701).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BUB1B
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for BubR1 Antibody [Janelia Fluor® 646]

  • Bub1A
  • BUBR1budding uninhibited by benzimidazoles 1 (yeast homolog), beta
  • budding uninhibited by benzimidazoles 1 homolog beta (yeast)
  • EC 2.7.11.1
  • hBUBR1
  • MAD3/BUB1-related protein kinase
  • MAD3LBUB1beta
  • Mitotic checkpoint kinase MAD3L
  • Protein SSK1
  • SSK1mitotic checkpoint serine/threonine-protein kinase BUB1 beta

Background

Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B), also known as BubR1, is a kinase involved in spindle checkpoint function. BUBR1 is essential for normal mitotic progression as it prevents cells from entering into anaphase too early. BUBR1 has been detected in human cancers. BubR-1 localizes to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation.

BubR1 antibodies are useful tools for cancer research and cell division studies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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BubR1 Antibody
[Janelia Fluor® ...
NB100-579JF646
BubR1 Antibody [Janelia Fluor® 646]
Species: Hu, Mu, Rt
Applications: WB, IP

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol BUB1B