BIK Antibody [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Bcl-2-interacting killer (BIK; also known as NBK, BP4 and BIP-1) is a 19 kDa member of the BH3-only subfamily, Bcl-2 family of proteins. It is widely expressed, and serves as an initiator of cell death. It apparently participates in apoptosis by sequestering antiapoptotic cytoplasmic proteins of the Bcl-2 family and in autophagy by regulating cytosolic calcium levels. Human BIK-1 is 160 amino acids (aa) in length. It contains one BH3 domain (aa 57‑74), a “death segment” (aa 121‑134) and a transmembrane domain (aa 136‑156). BIK is likely to embed in both outer mitochondrial and ER membranes. Over amino acids 1‑135, human BIK shares only 45% aa identity with mouse BIK.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Array AF5474

• BIK Antibodies
• BIK Proteins