beta ureidopropionase Antibody

Images

 
Western Blot: beta ureidopropionase Antibody [NBP3-17074] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10; Lane 2: RT4; Lane 3: U-251 MG; Lane 4: Human Plasma; Lane 5: Liver; Lane 6: Tonsil
Immunohistochemistry-Paraffin: beta ureidopropionase Antibody [NBP3-17074] - Staining of human liver shows high expression.
Immunohistochemistry-Paraffin: beta ureidopropionase Antibody [NBP3-17074] - Staining of human colon shows low expression as expected.
Immunohistochemistry-Paraffin: beta ureidopropionase Antibody [NBP3-17074] - Staining of human liver shows high expression.
Immunohistochemistry-Paraffin: beta ureidopropionase Antibody [NBP3-17074] - Analysis in human liver and colon tissues using Anti-UPB1 antibody. Corresponding UPB1 RNA-seq data are presented for the same tissues.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

beta ureidopropionase Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFEAAEEQLRRPRIVHVGL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
UPB1
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.2, 40% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for beta ureidopropionase Antibody

  • Beta-alanine synthase
  • beta-ureidopropionase
  • BUP-1
  • BUP1EC 3.5.1.6
  • N-carbamoyl-beta-alanine amidohydrolase
  • ureidopropionase, beta

Background

beta ureidopropionase encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol UPB1