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Bcl-10 Antibody (OTI4A8) [DyLight 405]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Flow, ICC/IF, IHC
Clone
OTI4A8
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-71398AF350
Alexa Fluor 405
NBP2-71398AF405
Alexa Fluor 488
NBP2-71398AF488
Alexa Fluor 532
NBP2-71398AF532
Alexa Fluor 594
NBP2-71398AF594
Alexa Fluor 647
NBP2-71398AF647
Alexa Fluor 700
NBP2-71398AF700
Alexa Fluor 750
NBP2-71398AF750
Allophycocyanin
NBP2-71398APC
Biotin
NBP2-71398B
CoraFluor 1
NBP2-71398CL1
DyLight 350
NBP2-71398UV
DyLight 488
NBP2-71398G
DyLight 550
NBP2-71398R
DyLight 594
NBP2-71398DL594
DyLight 650
NBP2-71398C
DyLight 680
NBP2-71398FR
DyLight 755
NBP2-71398IR
FITC
NBP2-71398F
HRP
NBP2-71398H
Janelia Fluor 525
NBP2-71398JF525
Janelia Fluor 549
NBP2-71398JF549
Janelia Fluor 585
NBP2-71398JF585
Janelia Fluor 635
NBP2-71398JF635
Janelia Fluor 646
NBP2-71398JF646
Janelia Fluor 669
NBP2-71398JF669
PE
NBP2-71398PE
PerCP
NBP2-71398PCP
Unconjugated
NBP2-02597
mFluor Violet 450 SE
NBP2-71398MFV450
mFluor Violet 500 SE
NBP2-71398MFV500
mFluor Violet 610 SE
NBP2-71398MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-02597
Azide and BSA Free
NBP2-71398
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Bcl-10 Antibody (OTI4A8) [DyLight 405] Summary

Immunogen
Full length recombinant protein of human Bcl-10 (NP_003912) produced in HEK293T cells.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
BCL10
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Bcl-10 Antibody (OTI4A8) [DyLight 405]

  • B-cell CLL/lymphoma 10CIPERCLAPB-cell lymphoma/leukemia 10
  • Bcl10
  • Bcl-10
  • CARD-containing apoptotic signaling protein
  • CARD-containing molecule enhancing NF-kappa-B
  • CARD-containing proapoptotic protein
  • CARD-like apoptotic protein
  • CARMEN
  • caspase-recruiting domain-containing protein
  • cCARMEN
  • c-E10
  • c-E10bcl-10
  • CED-3/ICH-1 prodomain homologous E10-like regulator
  • Cellular homolog of vCARMEN
  • cellular-E10
  • CIPER
  • CLAP
  • hCLAP
  • Mammalian CARD-containing adapter molecule E10
  • mE10
  • mE10CARD containing molecule enhancing NF-kB

Background

Bcl-10 is an adaptor protein with a caspase recruitment domain (CARD) that promotes apoptosis and activates pro-caspase 9 and NF-kB (1-2). Bcl-10 also interacts with other CARD domain containing proteins including CARD9, 10, 11 and 14. Bcl-10 is found to form a complex with MALT1, a protein known to be translocated in MALT lymphomas. Bcl-10 and MALT1 play a critical role in antigen receptor

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol BCL10