BCAT1 Antibody (OTI3F5)

This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq].

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: WB.

Showing Publications 1 - 2 of 2.

Publications using NBP2-01826	Applications	Species
Zhu Z, Achreja A, Meurs N et al. Tumour-reprogrammed stromal BCAT1 fuels branched-chain ketoacid dependency in stromal-rich PDAC tumours Nat Metab 2020-07-06 [PMID: 32694827] (WB, Human)	WB	Human
Li H, Ye D, Xie W et al. Defect of Branched-chain Amino Acid Metabolism Promotes the Development of Alzheimer's Disease by Targeting the mTOR Signaling Biosci. Rep. 2018-05-25 [PMID: 29802157] (Mouse)		Mouse

Array NBP2-01826

• BCAT1 Antibodies
• BCAT1 Lysates
• BCAT1 Proteins and Enzyme