BAG2 Antibody

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using NB100-1776	Applications	Species
Dai Q, Qian SB, Li HH et al. Regulation of the cytoplasmic quality control protein degradation pathway by BAG2. J Biol Chem 2005-11-18 [PMID: 16169850]

Array NB100-1776

• BAG2 Antibodies
• BAG2 Lysate
• BAG2 Proteins