Bag-1 Antibody (RM310) Summary
Additional Information |
Recombinant Monoclonal Antibody. |
Immunogen |
A peptide corresponding to residues near the N-terminus of human Bag-1 |
Specificity |
This antibody reacts to human Bag-1L. It does not cross react to Bag-1M or Bag-1S. |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
BAG1 |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry/ Immunofluorescence 1:200 - 1:1000
- Immunohistochemistry 1:500 - 1:2000
- Western Blot 1:1000 - 1:2000
|
Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles. |
Buffer |
50% Glycerol/PBS, 1% BSA |
Preservative |
0.09% Sodium Azide |
Purity |
Protein A purified |
Alternate Names for Bag-1 Antibody (RM310)
Background
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site, and alternative, downstream, AUG translation initiation sites.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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