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B7-H4 Antibody (2582H) [Allophycocyanin/Cy7]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications Flow
Clone
2582H
Clonality
Monoclonal
Host
Rabbit
Conjugate
Allophycocyanin/Cy7

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB21542U-100UG
Alexa Fluor 405
FAB21542V-100UG
Alexa Fluor 488
FAB21542G-100UG
Alexa Fluor 532
FAB21542X
Alexa Fluor 594
FAB21542T-100UG
Alexa Fluor 647
FAB21542R-100UG
Alexa Fluor 700
FAB21542N-100UG
Alexa Fluor 750
FAB21542S-100UG
Allophycocyanin
FAB21542A
Biotin
FAB21542B
DyLight 350
FAB21542D
DyLight 405
FAB21542E
DyLight 488
FAB21542K
DyLight 550
FAB21542L
DyLight 594
FAB21542M
DyLight 650
FAB21542W
DyLight 680
FAB21542Y
DyLight 755
FAB21542Z
FITC
FAB21542F
HRP
FAB21542H
Janelia Fluor 549
FAB21542I
Janelia Fluor 646
FAB21542J
PE
FAB21542P
PE/Atto594
FAB21542PEATT594
PE/Cy5.5
FAB21542PECY55
PE/Cy7
FAB21542PECY7
PerCP
FAB21542C
Unconjugated
MAB21542-100
mFluor Violet 450 SE
FAB21542MFV450
mFluor Violet 500 SE
FAB21542MFV500
mFluor Violet 610 SE
FAB21542MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB21542-100
Carrier Free
MAB21542-100
Carrier Free
MAB21542-SP
Carrier Free
FAB21542V-100UG
Carrier Free
FAB21542T-100UG
Carrier Free
FAB21542G-100UG
Carrier Free
FAB21542R-100UG
Carrier Free
FAB21542U-100UG
Carrier Free
FAB21542N-100UG
Carrier Free
FAB21542S-100UG
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B7-H4 Antibody (2582H) [Allophycocyanin/Cy7] Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse B7-H4
Phe29-Pro258
Accession # Q7TSP5
Specificity
Detects mouse B7-H4 in direct ELISAs. Detects human, mouse, and rat B7-H4 in Western blots.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Purity
Protein A or G purified from cell culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from cell culture supernatant

Alternate Names for B7-H4 Antibody (2582H) [Allophycocyanin/Cy7]

  • B7h.5
  • B7H4
  • B7-H4
  • B7H4T-cell costimulatory molecule B7x
  • B7S1
  • B7S1VCTN1
  • B7x
  • B7XPRO1291
  • FLJ22418
  • Immune costimulatory protein B7-H4
  • Protein B7S1
  • T cell costimulatory molecule B7x
  • V-set domain containing T cell activation inhibitor 1
  • V-set domain-containing T-cell activation inhibitor 1
  • Vtcn1

Background

B7H4 is a costimulatory protein which is reported to function as a negative regulator of T-cell mediated immunity. Although B7H4 binds an unknown receptor, it is thought to deliver an inhibitory signal to T-cells preventing their proliferation, cell cycle progression and interleukin-2 production. B7H4 deficient mice are only minimally affected, thus suggesting B7H4 is important in the fine tuning of the T-cell mediated immune response. B7H4 is expressed on activated T-cells, B-cells, monocytes and dendritic cells. Aberrant expression has been associated with cancers of the lung, breast and ovary in humans. B7H4 could be a useful prognostic marker in Renal Cell Carcinoma (RCC). There are three different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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B7-H4 Antibody (2582H) [Allophycocyanin/Cy7]
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