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Aurora C Antibody (OTI2B7)

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Western Blot: Aurora C Antibody (2B7) [NBP1-47663] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Aurora C (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell ...read more
Immunohistochemistry-Paraffin: Aurora C Antibody (2B7) [NBP1-47663] Staining of paraffin-embedded prostate tissue using anti-Aurora C mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Aurora C Antibody (2B7) [NBP1-47663] - Staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-Aurora C mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Aurora C Antibody (2B7) [NBP1-47663] - Staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-Aurora C mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Aurora C Antibody (2B7) [NBP1-47663] - Staining of paraffin-embedded bladder tissue using anti-Aurora C mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Aurora C Antibody (2B7) [NBP1-47663] - Staining of paraffin-embedded Carcinoma of bladder tissue using anti-Aurora C mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Aurora C Antibody (2B7) [NBP1-47663] - Staining of paraffin-embedded colon tissue using anti-Aurora C mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Aurora C Antibody (2B7) [NBP1-47663] - Staining of paraffin-embedded endometrium tissue using anti-Aurora C mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Aurora C Antibody (2B7) [NBP1-47663] - Staining of paraffin-embedded pancreas tissue using anti-Aurora C mouse monoclonal antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
OTI2B7
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.74 mg/ml

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Aurora C Antibody (OTI2B7) Summary

Immunogen
Full-length protein expressed in 293T cell transfected with human AURKC expression vector
Specificity
This antibody is specific for Homo sapiens aurora kinase C (AURKC), transcript variant 1.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
AURKC
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50
  • Immunohistochemistry-Paraffin 1:50
  • Western Blot 1:200-1:1000
Theoretical MW
35.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Concentration
0.74 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Aurora C Antibody (OTI2B7)

  • AIE2
  • AIE2AIK3
  • AIK3
  • AIRK3
  • ARK3
  • ARK-3
  • ARK3Serine/threonine-protein kinase aurora-C
  • AurC
  • AURKC
  • Aurora 3
  • Aurora C
  • aurora kinase CAurora/IPL1/Eg2 protein 2
  • Aurora/IPL1-related kinase 3
  • aurora-C
  • Aurora-related kinase 3
  • EC 2.7.11
  • EC 2.7.11.1
  • serine/threonine kinase 13 (aurora/IPL1-like)
  • serine/threonine-protein kinase 13
  • STK13
  • STK13ARK-3

Background

This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol AURKC
Entrez