ATF3 Antibody (CL1685)

Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Rat, Feline.

We have publications tested in 1 application: IHC-FrFl.

Showing Publications 1 - 3 of 3.

Publications using NBP2-34489	Applications	Species
Rotterman T, Haley-Johnson Z, Chopra T et al. Modulation of Central Synapse Remodelling after Remote Peripheral Injuries by the Ccl2-Ccr2 Axis and Microglia Available at SSRN 2023-05-24
Travis M. Rotterman, Zoë Haley-Johnson, Tana S. Pottorf, Tavishi Chopra, Ethan Chang, Shannon Zhang, William M. McCallum, Sarah Fisher, Haley Franklin, Myriam Alvarez, Timothy C. Cope, Francisco J. Alvarez Modulation of central synapse remodeling after remote peripheral injuries by the CCL2-CCR2 axis and microglia Cell reports 2024-03-08 [PMID: 38367237]
Calvo PM, de la Cruz RR, Pastor AM, Alvarez FJ Preservation of KCC2 expression in axotomized abducens motoneurons and its enhancement by VEGF Brain structure & function 2023-05-01 [PMID: 37005931] (IHC-FrFl, Rat, Feline)	IHC-FrFl	Rat, Feline

Array NBP2-34489

• ATF3 Antibodies
• ATF3 ELISA Kit
• ATF3 Lysates
• ATF3 Proteins