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Monkey Apolipoprotein E/ApoE ELISA Kit (Colorimetric)

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Monkey Apolipoprotein E/ApoE ELISA Kit (Colorimetric) [NBP2-77037] - Standard Curve Reference

Product Details

Summary
Reactivity PmSpecies Glossary
Applications ELISA
Suitable Sample Type
Serum, plasma, cell culture supernates, saliva and tissue homogenates
Standard Curve Range
6.25 ng/mL - 400 ng/mL
Sensitivity
1.56 ng/mL

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Monkey Apolipoprotein E/ApoE ELISA Kit (Colorimetric) Summary

Specificity
This assay has high sensitivity and excellent specificity for detection of Monkey Apolipoprotein E/ApoE. No significant cross-reactivity or interference between Monkey Apolipoprotein E/ApoE and analogues was observed.
Standard Curve Range
6.25 ng/mL - 400 ng/mL
Sensitivity
1.56 ng/mL
Assay Type
Competitive ELISA
Inter-Assay
%CV < 10
Intra-Assay
%CV < 8
Sample Volume
50 - 100 uL
Kit Type
ELISA Kit (Colorimetric)
Gene
APOE

Applications/Dilutions

Dilutions
  • ELISA

Packaging, Storage & Formulations

Storage
Store at 4°C.

Kit Components

Components
  1. Adhesive Strip (For 96 wells)
  2. Assay Plate (12 x 8 coated Microwells)
  3. HRP-Conjugate (100 x concentrate)
  4. HRP-Conjugate Diluent
  5. Instruction Manual
  6. Sample Diluent
  7. Standard (Freeze dried)
  8. Stop Solution
  9. TMB Substrate
  10. Wash Buffer (25 x concentrate)

Alternate Names for Monkey Apolipoprotein E/ApoE ELISA Kit (Colorimetric)

  • APOE
  • Apo-E
  • Apolipoprotein E
  • apolipoprotein E3
  • late onset)
  • MGC1571

Background

Apolipoprotein E (APOE) is an apolipoprotein located in chylomicrons and intermediate-density lipoproteins that is necessary for the normal catabolism of triglyceride-rich lipoprotein constituents in the liver. APOE has recently been shown to be involseveral biological processes other than lipoprotein transport, including cognition and immunoregulation.

Lipoproteins are responsible for carrying cholesterol and other fats through the bloodstream as little packages and are essential for the normal breakdown of these molecules. In particular, apolipoprotein E is a major component of specific lipoproteins called very low-density lipoproteins (VLDL). A major function of VLDLs is to remove excess cholesterol from the blood and carry it to the liver for processing. Maintaining normal levels of cholesterol is essential for the prevention of cardiovascular diseases, including heart attacks and strokes.

The three Apo E isoforms are strongly associated with cardiovascular disease and Alzheimer's disease, so ApoE antibodies have become useful tools for research in both of these areas.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol APOE