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AlphaB Crystallin/CRYAB Antibody (OTI6A9) [DyLight 650]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications Flow, ICC/IF, IHC, IP
Clone
OTI6A9
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 650

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-70454AF350
Alexa Fluor 405
NBP2-70454AF405
Alexa Fluor 488
NBP2-70454AF488
Alexa Fluor 532
NBP2-70454AF532
Alexa Fluor 594
NBP2-70454AF594
Alexa Fluor 647
NBP2-70454AF647
Alexa Fluor 700
NBP2-70454AF700
Alexa Fluor 750
NBP2-70454AF750
Allophycocyanin
NBP2-70454APC
Allophycocyanin/Cy7
NBP2-70454APCCY7
Biotin
NBP2-70454B
CoraFluor 1
NBP2-70454CL1
DyLight 350
NBP2-70454UV
DyLight 405
NBP2-70454V
DyLight 488
NBP2-70454G
DyLight 550
NBP2-70454R
DyLight 594
NBP2-70454DL594
DyLight 680
NBP2-70454FR
DyLight 755
NBP2-70454IR
FITC
NBP2-70454F
HRP
NBP2-70454H
Janelia Fluor 525
NBP2-70454JF525
Janelia Fluor 549
NBP2-70454JF549
Janelia Fluor 585
NBP2-70454JF585
Janelia Fluor 635
NBP2-70454JF635
Janelia Fluor 646
NBP2-70454JF646
Janelia Fluor 669
NBP2-70454JF669
PE
NBP2-70454PE
PE/Atto594
NBP2-70454PEATT594
PE/Cy5.5
NBP2-70454PECY55
PE/Cy7
NBP2-70454PECY7
PerCP
NBP2-70454PCP
Unconjugated
NBP1-47708
mFluor Violet 450 SE
NBP2-70454MFV450
mFluor Violet 500 SE
NBP2-70454MFV500
mFluor Violet 610 SE
NBP2-70454MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-47708
Azide and BSA Free
NBP2-70454
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AlphaB Crystallin/CRYAB Antibody (OTI6A9) [DyLight 650] Summary

Immunogen
Full length recombinant protein of human AlphaB Crystallin/CRYAB (NP_001876) produced in HEK293T cells.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CRYAB
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for AlphaB Crystallin/CRYAB Antibody (OTI6A9) [DyLight 650]

  • alpha B crystallin
  • alpha(B)-crystallin
  • AlphaB Crystallin
  • alpha-crystallin B chain
  • CRYA2
  • CRYA2alpha crystallin B chain
  • CRYAB
  • crystallin, alpha B
  • CTPP2
  • Heat shock protein beta-5
  • heat-shock 20 kD like-protein
  • HSPB5
  • Renal carcinoma antigen NY-REN-27
  • Rosenthal fiber component

Background

Crystallin AB is a member of the small heat shock protein family and expressed in several tissues including brain, kidney cardiac and skeletal muscle. Crystallin AB functions as a molecular chaperone and in intracellular architecture. Crystallin AB has shown to have interactions with CRYAA, CRYGC, CRYBB2, CRYBA1 and HSPB8. Defects in crystalline AB have been linked to cause myopathy myofibrillar type 2, cataract posterior polar type 2, and myopathy myofibrillar fatal infantile hypertonic alpha-B crystallin-related (MFMFIH-CRYAB).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CRYAB