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Acetylcholinesterase/ACHE Assay Kit (Fluorometric)

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Acetylcholinesterase/ACHE Assay Kit (Fluorometric) [KA4132] - The standard curve is for the purpose of demonstration only and should not be used to calculate unknowns. A standard curve should be generated each time the ...read more

Product Details

Summary
Reactivity RtSpecies Glossary
Applications Func
Suitable Sample Type
Biological Samples
Standard Curve Range
0.1 to 100 mU/mL
Sensitivity
0.1 mU/mL

Order Details

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Acetylcholinesterase/ACHE Assay Kit (Fluorometric) Summary

Description
Quality control test: Standard curve Acetylcholinesterase Assay Kit (Red Fluorescence) is a one-step fluorometric assay for the detection of AChE activity.
Specificity
The kit is an optimized 'mix and read' assay that provides a simple one- step fluorimetric assay to detect as little as 0.01 mU AChE in a 100 uL assay volume (0.1 mU/mL). Its signal can be easily read with a fluorescence microplate reader at Ex/Em = ~540/590 nm or an absorbance microplate reader at ~575 nm.
Standard Curve Range
0.1 to 100 mU/mL
Sensitivity
0.1 mU/mL
Assay Type
Fluorometric
Sample Volume
50 uL
Kit Type
Assay Kit (Fluorometric)
Gene
ACHE

Applications/Dilutions

Dilutions
  • Functional
Publications
Read Publications using KA4132.

Packaging, Storage & Formulations

Storage
Store at -20C.

Kit Components

Components
  1. Acetylcholine
  2. Acetylcholinesterase Probe (lyophilized powder)
  3. Acetylcholinesterase Standard (5 units)
  4. Amplite Red
  5. Assay Buffer
  6. Dilution Buffer
  7. DMSO

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Acetylcholinesterase/ACHE Assay Kit (Fluorometric)

  • acetylcholinesterase (Yt blood group)
  • Acetylcholinesterase
  • ACHE
  • apoptosis-related acetylcholinesterase
  • ARACHE
  • EC 3.1.1
  • EC 3.1.1.7
  • N-ACHE
  • Yt blood group
  • YT

Background

Acetylcholinesterase (AChE) is one of the most crucial enzymes for nerve response and function. AChE degrades the neurotransmitter acetylcholine (ACh) into choline and acetic acid. It is mainly found at neuromuscular junctions and cholinergic synapses in the central nervous system, where its activity serves to terminate the synaptic transmission. AChE inhibitors are among the key drugs approved for Alzheimer's disease (AD) and myasthenia gravis.Acetylcholinesterase (AChE) is one of the most crucial enzymes for nerve response and function. AChE degrades the neurotransmitter acetylcholine (ACh) into choline and acetic acid. It is mainly found at neuromuscular junctions and cholinergic synapses in the central nervous system, where its activity serves to terminate the synaptic transmission. AChE inhibitors are among the key drugs approved for Alzheimer's disease (AD) and myasthenia gravis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Kits are guaranteed for 6 months from date of receipt.

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Publications for Acetylcholinesterase/ACHE Kit (KA4132)(3)

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Bioinformatics

Gene Symbol ACHE