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ACE/CD143 Antibody (171417) [Janelia Fluor® 635]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IP, CyTOF-ready
Clone
171417
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 635

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB929U-100UG
Alexa Fluor 405
FAB929V-100UG
Alexa Fluor 488
FAB929G-100UG
Alexa Fluor 532
FAB929X
Alexa Fluor 594
FAB929T-100UG
Alexa Fluor 647
FAB929R-100UG
Alexa Fluor 700
FAB929N-100UG
Alexa Fluor 750
FAB929S-100UG
Allophycocyanin
FAB929A
Allophycocyanin/Cy7
FAB929APCCY7
Biotin
BAM929
CoraFluor 1
FAB929CL1
DyLight 350
FAB929D
DyLight 405
FAB929E
DyLight 488
FAB929K
DyLight 550
FAB929L
DyLight 594
FAB929M
DyLight 650
FAB929W
DyLight 680
FAB929Y
DyLight 755
FAB929Z
FITC
FAB929F
HRP
FAB929H
Janelia Fluor 525
FAB929JF525
Janelia Fluor 549
FAB929I
Janelia Fluor 585
FAB929JF585
Janelia Fluor 646
FAB929J
Janelia Fluor 669
FAB929JF669
PE/Atto594
FAB929PEATT594
PE/Cy5.5
FAB929PECY55
PE/Cy7
FAB929PECY7
PerCP
FAB929C
Phycoerythrin
FAB929P
Unconjugated
MAB929
mFluor Violet 450 SE
FAB929MFV450
mFluor Violet 500 SE
FAB929MFV500
mFluor Violet 610 SE
FAB929MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB929
Carrier Free
FAB929P
Carrier Free
MAB929
Carrier Free
MAB929-SP
Carrier Free
FAB929S-100UG
Carrier Free
FAB929R-100UG
Carrier Free
FAB929N-100UG
Carrier Free
FAB929G-100UG
Carrier Free
FAB929V-100UG
Carrier Free
FAB929U-100UG
Carrier Free
FAB929T-100UG
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ACE/CD143 Antibody (171417) [Janelia Fluor® 635] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human ACE/CD143
aa 30-1261
Specificity
Detects human ACE/CD143 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human ACE-2 is observed. Detects the surface expression of human ACE on full length ACE transfectants, but not on control transfectants by flow cytometry.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ACE
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunoprecipitation
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for ACE/CD143 Antibody (171417) [Janelia Fluor® 635]

  • ACE
  • ACE1angiotensin converting enzyme, somatic isoform
  • angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • carboxycathepsin
  • CD143 antigen
  • CD143
  • DCP
  • DCP1
  • DCP1angiotensin-converting enzyme
  • dipeptidyl carboxypeptidase 1
  • Dipeptidyl carboxypeptidase I
  • EC 3.2.1.-
  • EC 3.4.15.1
  • Kininase II
  • MGC26566
  • MVCD3
  • peptidase P
  • testicular ECA

Background

ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ACE