14-3-3 epsilon Antibody

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: IF/IHC, IP.

Showing Publications 1 - 2 of 2.

Publications using NBP1-32695	Applications	Species
O'Sullivan D, Dowling P, Joyce H et al. A novel inhibitory anti-invasive MAb isolated using phenotypic screening highlights AnxA6 as a functionally relevant target protein in pancreatic cancer. Br. J. Cancer. 2017-10-24 [PMID: 28881357] (IP, Human)	IP	Human
Dowling P, Moran B, Mcauley E et al. Quantitative label-free mass spectrometry analysis of formalin-fixed, paraffin-embedded tissue representing the invasive cutaneous malignant melanoma proteome. Oncology Letters [PMID: 27899996] (IF/IHC)	IF/IHC

Array NBP1-32695

• 14-3-3 epsilon Antibodies
• 14-3-3 epsilon Lysate
• 14-3-3 epsilon Proteins