| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | MAB4227-SP | |||
| Carrier Free | FAB4227S-100UG | |||
| Carrier Free | FAB4227R-100UG | |||
| Carrier Free | FAB4227N-100UG | |||
| Carrier Free | FAB4227V-100UG | |||
| Carrier Free | FAB4227U-100UG | |||
| Carrier Free | FAB4227T-100UG | |||
| Carrier Free | FAB4227G-100UG | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | AF4227-SP | |||
| Conjugate | Catalog # | Availability | Size | Price |
|---|---|---|---|---|
| Alexa Fluor 350 | FAB7167U-100UG | |||
| Alexa Fluor 405 | FAB7167V-100UG | |||
| Alexa Fluor 488 | FAB7167G-100UG | |||
| Alexa Fluor 594 | FAB7167T-100UG | |||
| Alexa Fluor 647 | FAB7167R-100UG | |||
| Alexa Fluor 700 | FAB7167N-100UG | |||
| Alexa Fluor 750 | FAB7167S-100UG | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | MAB7167-SP | |||
| Carrier Free | FAB7167V-100UG | |||
| Carrier Free | FAB7167U-100UG | |||
| Carrier Free | FAB7167T-100UG | |||
| Carrier Free | FAB7167S-100UG | |||
| Carrier Free | FAB7167R-100UG | |||
| Carrier Free | FAB7167N-100UG | |||
| Carrier Free | FAB7167G-100UG | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | MAB8399-SP | |||
| Carrier Free | FAB8399V-100UG | |||
| Carrier Free | FAB8399U-100UG | |||
| Carrier Free | FAB8399T-100UG | |||
| Carrier Free | FAB8399S-100UG | |||
| Carrier Free | FAB8399R-100UG | |||
| Carrier Free | FAB8399N-100UG | |||
| Carrier Free | FAB8399G-100UG | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | MAB8399 | |||
| Carrier Free | MAB8399-SP | |||
| Carrier Free | FAB8399V-100UG | |||
| Carrier Free | FAB8399U-100UG | |||
| Carrier Free | FAB8399T-100UG | |||
| Carrier Free | FAB8399S-100UG | |||
| Carrier Free | FAB8399R-100UG | |||
| Carrier Free | FAB8399N-100UG | |||
| Carrier Free | FAB8399G-100UG | |||
![Impact of CXCR7 over-expression on the E2-dependent and -independent growth of MCF-7 cells.MCF-7 cells were transiently transfected with either a control expression vector or one containing the human CXCR7 open reading frame. (A) Total protein extracts were prepared 48 h after transfection, and a Western blot analysis was performed to confirm CXCR7 over-expression. (B) Transfected cells were cultured in the presence of EtOH (−) or 10−8 M E2 (+) for seven days. E2-dependent and E2-independent cell growth rates were then evaluated by cell count of three independent experiments (n = 3). The results are expressed as a percentage of the relative cell number obtained from control cells treated with E2 (considered as 100%). Significant differences (p<0.05) between transfected cells in the absence of E2 are indicated by an asterisk and between transfected cells in the presence of E2 by a sharp symbol. (C) A proposed model for the involvement of the CXCL12 signaling axis in E2-dependent and -independent cell growth is shown. The binding of CXCL12 to CXCR4 and CXCR7 leads to the stimulation of cell growth through diverse pathways [28]. CXCR7 can also modulate CXCL12 availability by removing the chemokine from the extracellular space (left panel). Estrogens could stimulate cell growth by favoring the activation of CXCL12 through CXCR4 and reducing the expression of CXCR7 (right panel). Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/21695171), licensed under a CC-BY license. Not internally tested by R&D Systems.](http://images.novusbio.com/fullsize/mab42273_human-cxcr7-rdc-1-mab-clone-11g8-812025557241.jpg)
