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Joint Laxity: Disease Bioinformatics

Research of Joint Laxity has been linked to Ehlers-danlos Syndrome, Pain, Dislocations, Hypermobility Syndrome, Connective Tissue Diseases. The study of Joint Laxity has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Joint Laxity include Translation, Pathogenesis, Proprioception, Ossification, Dentinogenesis. These pathways complement our catalog of research reagents for the study of Joint Laxity including antibodies and ELISA kits against AP, NOTCH, ACLY, COL1A1, COL1A2.

Top Research Reagents

We have 954 products for the study of Joint Laxity that can be applied to Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

NBP3-41235
Western Blot: Collagen V alpha 2 Antibody [NBP3-41235] - Sample: Recombinant protein.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

NBP1-31336
Knockdown Validated: Fumarase Antibody [NBP1-31336] - Non-transfected (-) and transfected (+) 293T whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with Fumarate hydratase antibody. HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.Western Blot: Fumarase Antibody [NBP1-31336] - Representative western blots showing protein expression of fumarase and key enzymes in OXPHOS. VDAC was used as a loading control (n = 3). Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/srep22788) licensed under a CC-BY license.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     1 Review

1 Publication
H00010963-M35
Western Blot: STI1 Antibody (2E11) [H00010963-M35] - Analysis of STIP1 expression in human ovarian cancer.Immunocytochemistry/Immunofluorescence: STI1 Antibody (2E11) [H00010963-M35] - Analysis of monoclonal antibody to STIP1 on HeLa cell. Antibody concentration 10 ug/ml

Mouse Monoclonal
Species Human
Applications WB, ELISA, Flow

4 Publications
NBP1-05118
Western Blot: Collagen V Antibody (1E2-E4/Col5) [NBP1-05118] - Staining with 1E2-E4/Col5 on Dog Type I, III, V and Human Type I, III, and V in rows 1-6 respectively. (1. Werkmeister)

Mouse Monoclonal
Species Human, Porcine, Bovine
Applications WB, ELISA, IHC

2 Publications
NBP1-84722
Immunohistochemistry-Paraffin: Fibrillin 1 Antibody [NBP1-84722] - Staining in human cervix, uterine and cerebral cortex tissues . Corresponding FBN1 RNA-seq data are presented for the same tissues.Immunocytochemistry/Immunofluorescence: Fibrillin 1 Antibody [NBP1-84722] - Staining of human cell line U-251 MG shows localization to cytosol. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

4 Publications
NBP1-88071
Immunohistochemistry-Paraffin: Titin Antibody [NBP1-88071] - Analysis in human skeletal muscle and liver tissues. Corresponding TTN RNA-seq data are presented for the same tissues.Immunocytochemistry/Immunofluorescence: Titin Antibody [NBP1-88071] - SMYD2 Cys13 glutathionylation or oxidation reduces myofibril integrity. Monitoring the myofibril alignment in rat neonatal cardiomyocytes upon incubation of AMA (2 ug/mL) for 12 h: no expression of SMYD2 WT. Immunostainings were done by using antibodies to SMYD2, HA (green), or titin (alpha-titin-NT, red). About 30 cells were photographed and examined for myofibril alignment or directionality by FiberFit software. 34 Images represent the major myofibril structure in individual conditions. Scale bars, 10 um. Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/s41467-018-06786-x), licensed under a CC-BY license.

Rabbit Polyclonal
Species Human, Rat
Applications ICC/IF, IHC, IHC-P

4 Publications
NBP1-90267
Western Blot: ATP Citrate Lyase Antibody [NBP1-90267] - Analysis using Anti-ACLY antibody NBP1-90267 (A) shows similar pattern to independent antibody NBP1-90268 (B).Immunocytochemistry/Immunofluorescence: ATP Citrate Lyase Antibody [NBP1-90267] - Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NBP1-97503

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

8 Publications
NB600-594
Immunohistochemistry: Collagen III alpha 1/COL3A1 Antibody [NB600-594] - Tissue: right lobe of the liver section. A:Central Vein (CV) fibrosis, B: Non-fibrotic CV, C: Perisinusodial fibrosis, D: Non-fibrotic area, E: Protat tract fibrosis, F: Septal fibrosis (arrow). Fixation: FFPE. Antigen retrieval: not required. Primary antibody: Anti-collagen type I at 1:500 for 4 degrees Celsius for 24hr. Secondary antibody: Peroxidase biotin-streptavidin rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: Anti-collagen type III is intra and extracellular. Staining: 3.3'-diaminobenzidine tetrahydrochloride was used as the chromogen. Nuclei were counterstained purple with hematoxylin.Western Blot: Collagen III alpha 1/COL3A1 Antibody [NB600-594] - Lane 1: Human Collagen III Load: 100 ng per lane Primary antibody: Collagen III Antibody at 1:1000 o/n at 4C Secondary antibody: DyLight 649 Goat anti-rabbit at 1:20,000 for 30 min at RT Block: incubated with blocking buffer for 30 min at RT Predicted/Observed size: 138 kDa/138 kDa.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ELISA

     7 Reviews

50 Publications
AF6999
Western blot shows lysates of human heart tissue. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human Tenascin X Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6999) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # <a class=Tenascin X was detected in immersion fixed paraffin-embedded sections of human lung mesothelioma using Sheep Anti-Human Tenascin X Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6999) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <a class=

Sheep Polyclonal
Species Human
Applications WB, Simple Western, IHC

1 Publication
NBP2-38770
Western Blot: PLOD1 Antibody [NBP2-38770] - Analysis in human cell line U-251 MG and human cell line RT-4.Western Blot: PLOD1 Antibody [NBP2-38770] - SC65 directly interacts with lysyl-hydroxylase 1 (LH1). Western blot of primary calvarial osteoblast and skin fibroblast lysates from WT and Sc65KO 3 day-old mice (N = 2) showing significantly decreased levels of LH1 protein in Sc65KO samples. Densitometric quantification of LH1 protein normalized to beta-actin from the western blot shown above (*p<0.05; error bars represent SD). All experiments were performed at least 3 times.  Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pgen.1006002), licensed under a CC-BY license.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC-P

3 Publications
DCMP0
N/A COMP/Thrombospondin-5 [HRP]N/A COMP/Thrombospondin-5 [HRP]


Species Human
Applications ELISA

12 Publications
NBP2-47427
Western Blot: Hsp70 interacting protein HIP Antibody [NBP2-47427] - Analysis using Anti-ST13 antibody NBP2-47427 (A) shows similar pattern to independent antibody NBP2-48865 (B).Immunocytochemistry/Immunofluorescence: Hsp70 interacting protein HIP Antibody [NBP2-47427] - Immunofluorescent staining of human cell line Hep G2 shows localization to cytosol.

Rabbit Polyclonal
Species Human, Canine
Applications WB, ICC/IF, IHC

1 Publication
NB600-408
Rat colon tissue stained with Collagen I antibody (red) and Hoechst (blue). IHC-P image submitted by a verified customer review.Myofibroblast differentiation requires CD271/NGF activation. Representative alphaSMA (red) and COLLAGEN 1 (red) immunostaining with DAPI (blue) in non-treated (control), TGFbeta-treated cells with or without gamma-secretase inhibitor. Scale bars: 50 um Image collected and cropped by CiteAb from the following publication (//www.nature.com/articles/s41467-019-09992-3) licensed under a CC-BY license.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, FLISA

     16 Reviews

322 Publications
NBP2-55104
Western Blot: VPS13B Antibody [NBP2-55104] - Analysis in human ovary tissue.Immunocytochemistry/Immunofluorescence: VPS13B Antibody [NBP2-55104] - Staining of human cell line U-2 OS shows localization to cell junctions. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF

     1 Review

NBP2-92790
Immunocytochemistry/Immunofluorescence: COL1A2 Antibody [NBP2-92790] - Analysis of NIH/3T3 cells using Collagen I/COL1A2 antibody at dilution of 1:25. Blue: DAPI for nuclear staining.Immunohistochemistry-Paraffin: COL1A2 Antibody [NBP2-92790] - Human placenta using Collagen I/COL1A2 Rabbit pAb (A5786) at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

1 Publication
NB110-40548
Western Blot: Pescadillo Antibody [NB110-40548] - Detection of human Pescadillo by western blot. Samples: Whole cell lysate (50 ug) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-Pescadillo antibody NB110-40548 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.Immunohistochemistry: Pescadillo Antibody [NB110-40548] - Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti- Pescadillo used at a dilution of 1:200 (1ug/ml). Detection: DAB

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication
NBP3-12262
Immunohistochemistry-Paraffin: GLUT10 Antibody [NBP3-12262] - IHC of NBP3-12262 with mouse brain. Short perfusion followed by 1 hour post-fixation and immersion in sucrose. 1:100 antibody dilution in DiluObuffer.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF


Related Genes

Joint Laxity has been researched against:

Related PTMs

Joint Laxity has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Joint Laxity is also known as Hypermobility, Joint, Joint Hypermobility, Joint Laxities, Laxity, Joint.