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Hypermobility Syndrome: Disease Bioinformatics

Research of Hypermobility Syndrome has been linked to Joint Laxity, Pain, Ehlers-danlos Syndrome, Connective Tissue Diseases, Arthralgia. The study of Hypermobility Syndrome has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Hypermobility Syndrome include Proprioception, Aging, Reflex, Pathogenesis, Defecation. These pathways complement our catalog of research reagents for the study of Hypermobility Syndrome including antibodies and ELISA kits against VAS, GROWTH HORMONE, ARSA, BLM, CTSC.

Top Research Reagents

We have 1408 products for the study of Hypermobility Syndrome that can be applied to Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

Arylsulfatase A/ARSA Antibody

NBP1-00154

Western Blot: Arylsulfatase A/ARSA Antibody [NBP1-00154] - Western blot analysis of Mouse testes lysate (A) + peptide (B) with antibody at 1 ug/mL and Rat testes lysate (C) + peptide (D) with antibody at 0.3 ug/mL, 35ug protein in RIPA buffer. Detected by chemiluminescence.

Immunocytochemistry/Immunofluorescence: Arylsulfatase A/ARSA Antibody [NBP1-00154] - Immunofluorescence analysis of paraformaldehyde fixed HeLa cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing Golgi apparatus staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL).

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

1 Publication

Bestrophin 1 Antibody (E6-6) - BSA Free

NB300-164

Western Blot: Bestrophin 1 Antibody (E6-6) - BSA Free [NB300-164] - Western blot analysis of the normal and mutant human Best1 protein in transiently transfected MDCK cells. Best1 proteins are detectable as a 68 kDa band in all transfected cells, but not in non-transfected controls (MDCK lane). Actin bands are shown to indicate equal loading of cell lysates. Image collected and cropped by CiteAb from the following publication (https://www.mdpi.com/1422-0067/14/7/15121), licensed under a CC-BY license.

Immunocytochemistry/Immunofluorescence: Bestrophin 1 Antibody (E6-6) - BSA Free [NB300-164] - X-Z confocal single image scan of transiently transfected cells with different BEST1 cDNA constructs showing mislocalization of mutants Y85H, Q96R, L100R and Y227N. Cells were stained for Best1 (green), beta-catenin (red) and nuclei (blue). Scale bar = 10 um. Image collected and cropped by CiteAb from the following publication (https://www.mdpi.com/1422-0067/14/7/15121), licensed under a CC-BY license.

Mouse Monoclonal
Species Human, Mouse, Porcine
Applications WB, ICC/IF, IHC

1 Review

49 Publications

RhoD Antibody

NBP1-58359

Western Blot: RhoD Antibody [NBP1-58359] - Transfected 293T, Antibody Titration: 0.2-1 ug/ml

Immunohistochemistry: RhoD Antibody [NBP1-58359] - Human Liver Tissue Observed Staining: Cytoplasm in sinusoids of liver Primary Antibody Concentration: 1 : 100 Other Working Concentrations: 1/600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1 : 200 Magnification: 20X Expos

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NRK Antibody

NBP1-84121

Immunohistochemistry-Paraffin: NRK Antibody [NBP1-84121] - Staining of human kidney shows moderate granular cytoplasmic positivity in cells in tubules.

Immunohistochemistry-Paraffin: NRK Antibody [NBP1-84121] - Staining of human placenta shows cytoplasmic positivity in trophoblastic cells and decidua cells.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

1 Publication

Blooms Syndrome Protein Blm Antibody

NBP1-89929

Immunocytochemistry/Immunofluorescence: Blooms Syndrome Protein Blm Antibody [NBP1-89929] - Staining of human cell line A-431 shows positivity in nucleus and cytoplasm. Antibody staining is shown in green.

Immunohistochemistry-Paraffin: Blooms Syndrome Protein Blm Antibody [NBP1-89929] - Staining of human stomach shows strong nuclear positivity in glandular cells.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

1 Review

4 Publications

Dystrophin Antibody

NBP1-89953

Immunohistochemistry-Paraffin: Dystrophin Antibody [NBP1-89953] - Staining in human skeletal muscle and tonsil tissues . Corresponding DMD RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: Dystrophin Antibody [NBP1-89953] - Staining of human heart muscle shows strong membranous positivity in myocytes.

Rabbit Polyclonal
Species Human, Mouse
Applications ICC/IF, IHC, IHC-P

4 Publications

SLC14A1 Antibody

NBP2-31781

Immunohistochemistry: SLC14A1 Antibody [NBP2-31781] - Staining of human urinary bladder shows moderate membranous positivity in urothelial cells.

Immunohistochemistry-Paraffin: SLC14A1 Antibody [NBP2-31781] - Staining of human urinary bladder shows strong cytoplasmic positivity in erythrocytes.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

Collagen III alpha 1/COL3A1 Antibody

NB600-594

Immunohistochemistry: Collagen III alpha 1/COL3A1 Antibody [NB600-594] - Tissue: right lobe of the liver section. A:Central Vein (CV) fibrosis, B: Non-fibrotic CV, C: Perisinusodial fibrosis, D: Non-fibrotic area, E: Protat tract fibrosis, F: Septal fibrosis (arrow). Fixation: FFPE. Antigen retrieval: not required. Primary antibody: Anti-collagen type I at 1:500 for 4 degrees Celsius for 24hr. Secondary antibody: Peroxidase biotin-streptavidin rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: Anti-collagen type III is intra and extracellular. Staining: 3.3'-diaminobenzidine tetrahydrochloride was used as the chromogen. Nuclei were counterstained purple with hematoxylin.

Western Blot: Collagen III alpha 1/COL3A1 Antibody [NB600-594] - Lane 1: Human Collagen III Load: 100 ng per lane Primary antibody: Collagen III Antibody at 1:1000 o/n at 4C Secondary antibody: DyLight 649 Goat anti-rabbit at 1:20,000 for 30 min at RT Block: incubated with blocking buffer for 30 min at RT Predicted/Observed size: 138 kDa/138 kDa.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ELISA

7 Reviews

50 Publications

Cathepsin C/DPPI Antibody [Unconjugated]

AF1034

Western blot shows lysates of mouse liver tissue and mouse spleen tissue. PVDF membrane was probed with 0.25 µg/mL of Goat Anti-Mouse Cathepsin C/DPPI Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1034) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=

Western blot shows lysates of mouse lung tissue and rat lung tissue. PVDF membrane was probed with 1 µg/mL of Goat Anti-Mouse Cathepsin C/DPPI Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1034) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=

Goat Polyclonal
Species Mouse, Rat
Applications WB, Simple Western, IHC

14 Publications

Tenascin X Antibody [Unconjugated]

AF6999

Western blot shows lysates of human heart tissue. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human Tenascin X Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6999) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # <a class=

Tenascin X was detected in immersion fixed paraffin-embedded sections of human lung mesothelioma using Sheep Anti-Human Tenascin X Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6999) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <a class=

Sheep Polyclonal
Species Human
Applications WB, Simple Western, IHC

1 Publication

IRF1 Antibody [Unconjugated]

AF4715

Western blot shows lysates of NIH-3T3 mouse embryonic fibroblast cell line. Gels were loaded with 30 µg of whole cell lysate (WCL), 20 µg of cytoplasmic (Cyto), and 10 µg of nuclear extracts (Nuc). PVDF membrane was probed with 1 µg/mL Mouse IRF1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4715) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=

Whole cell lysates from MCF7 and SUM159 cells were loaded with 50 ug/lane.10% SDS-PAGE. IRF1 Antibody (AF4715) was used for primary antibody: 1:1000, 4℃, overnight. Image from a verified customer review.

Goat Polyclonal
Species Mouse
Applications WB

1 Review

2 Publications

IL1RAPL2 Antibody [Unconjugated]

AF1007

HepG2 human hepatocellular carcinoma cell line was stained with Goat Anti-Human IL1RAPL2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1007, filled histogram) or control antibody (Catalog&nbsp;# <a class=

Hepa&nbsp;1‑6 mouse hepatoma cell line was stained with Goat Anti-Human IL1RAPL2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1007, filled histogram) or control antibody (Catalog&nbsp;# <a class=

Goat Polyclonal
Species Human
Applications WB, Flow, IHC

COMP/Thrombospondin-5 [HRP]

DCMP0

N/A COMP/Thrombospondin-5 [HRP]

N/A COMP/Thrombospondin-5 [HRP]

Species Human
Applications ELISA

12 Publications

IGF-I/IGF-1 [Unconjugated]

291-G1

Recombinant Human IGF-I/IGF-1 (Catalog # 291-G1) stimulates proliferation in the MCF-7 human breast cancer cell line. The ED<sub>50</sub> for this effect is 0.3‑1.5&nbsp;ng/mL.

1 μg/lane of Recombinant Human IGF-I/IGF-1 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at&nbsp;7&nbsp;kDa.

Species Human
Applications BA

224 Publications

Rhodopsin Antibody (4D2)

NBP2-59690

Western Blot: Rhodopsin Antibody (4D2) [NBP2-59690] - Western Blot analysis of Human A549 cells showing detection of ~38.9kDa Rhodopsin protein using Mouse Anti-Rhodopsin Monoclonal Antibody, Clone 4D2 (NBP2-59690). Lane 1: MW ladder. Lane 2: Human A549 Cells 15 ug). Load: 15 ug. Block: 5% Skim Milk Powder in TBST. Primary Antibody: Mouse Anti-Rhodopsin Monoclonal Antibody (NBP2-59690) at 1:1000 for 2.5 hours at RT with shaking . Secondary Antibody: Goat anti-mouse IgG:HRP at 1:1000 for 1 hour at RT with shaking . Color Development: Chemiluminescent for HRP (Moss) for 5 min in RT. Predicted/Observed Size: ~38.9kDa. Other Band(s): Band appears at ~75 kDa indicating detection of the Rhodopsin dimer.

Immunohistochemistry: Rhodopsin Antibody (4D2) [NBP2-59690] - Immunohistochemistry analysis using Mouse Anti-Rhodopsin Monoclonal Antibody, Clone 4D2 (NBP2-59690). Tissue: retina. Species: Mouse. Primary Antibody: Mouse Anti-Rhodopsin Monoclonal Antibody (NBP2-59690) at 1:1000. Secondary Antibody: FITC Goat Anti-Mouse (green). Counterstain: DAPI (blue) nuclear stain. Localization: Staining of photoreceptor outer segment (OS). Other layers of the retina: IS inner segment; ONL outer nuclear layer; OPL outer plexiform layer; INL inner nuclear layer; IPL inner plexiform layer; GCL ganglion cell layer..

Mouse Monoclonal
Species Amphibian, Avian, Fish
Applications WB, ELISA, ICC/IF

1 Review

6 Publications

TBX4 Antibody

NBP2-85889

Western Blot: TBX4 Antibody [NBP2-85889] - WB Suggested Anti-TBX4 Antibody Titration: 0.2-1 ug/ml. Positive Control: HepG2 cell lysate

Western Blot: TBX4 Antibody [NBP2-85889] - Host: Rabbit. Target: TBX4. Positive control (+): Human lung (LU). Negative control (-): MCF7 (N10). Antibody concentration: 1ug/ml

Rabbit Polyclonal
Species Human
Applications WB

COL1A2 Antibody - Azide and BSA Free

NBP2-92790

Immunocytochemistry/Immunofluorescence: COL1A2 Antibody [NBP2-92790] - Analysis of NIH/3T3 cells using Collagen I/COL1A2 antibody at dilution of 1:25. Blue: DAPI for nuclear staining.

Immunohistochemistry-Paraffin: COL1A2 Antibody [NBP2-92790] - Human placenta using Collagen I/COL1A2 Rabbit pAb (A5786) at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

1 Publication

Related Genes

Hypermobility Syndrome has been researched against:

Related Pathways

Hypermobility Syndrome has been linked to:

Related Diseases

Hypermobility Syndrome has been studied in relation to diseases such as:

Alternate Names

Hypermobility Syndrome is also known as hypermobility syndrome, hypermobility syndrome (disorder), benign joint hypermobility.

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