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Cytochrome c Products

Antibodies
Cytochrome c Antibody (6H2.B4 ...
Cytochrome c Antibody (6H2.B4)
NBP2-24872
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IP, B/N
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
Cytochrome c Antibody
Cytochrome c Antibody
Species: Hu, Mu, Rt, Ca, Dr, Po, Bv, Pm
Applications: WB, Simple Western, IHC
Host: Rabbit Polyclonal
ELISA Kits
Rat/Mouse Cytochrome c Quanti ...
Rat/Mouse Cytochrome c Quantikine ...
MCTC0
Species: Mu, Rt
Applications: ELISA
Human Cytochrome c Quantikine ...
Human Cytochrome c Quantikine ELIS...
DCTC0
Species: Hu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Human Cytochrome c ELISA Kit ...
Human Cytochrome c ELISA Kit (Colo...
NBP1-91263
Species: Hu
Applications: ELISA
Lysates
Cytochrome c Overexpression L ...
Cytochrome c Overexpression Lysate
NBL1-09662
Species: Hu
Applications: WB
Proteins
Human Cytochrome c (Human Hea ...
Human Cytochrome c (Human Heart Ti...
709-CCH
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  

Description

In addition to its well-known role in electron-transport, cytochrome c (CYT) has been identified as a mediator of apoptosis or programmed cell death (1). Cytochrome c translocates from mitochondria into the cytoplasm in the early phases of apoptosis and plays a role in initiation of the apoptotic proteolytic cascade bay activating caspase-3 (2). Cytochrome c has been shown to bind Apaf-1. Apaf-1 has also been shown to activate capase-3 (3).

Bioinformatics

Entrez Mouse
Rat
Human
Uniprot Human
Human
Human
Human
Mouse
Rat
Human
Product By Gene ID 54205
Alternate Names
  • CYCHCS
  • cytochrome c
  • cytochrome c, somatic
  • THC4

Research Areas for Cytochrome c

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cellular Markers
Cholesterol Metabolism
Core ESC-Like Genes
Lipid and Metabolism
Mitochondrial Markers
Stem Cell Markers

Related Cytochrome c Blog Posts

Check out the latest blog posts on Cytochrome c.
The use of apoptosis antibodies and controls in cell death research
Apoptosis is a method of programmed cell death that is notably characterized by a morphological change in cellular nuclei and membrane appearance.  Not to be confused with necrosis, apoptosis is a pathway that is induced by a variety of factors tha...    Read more.
The Role of the Caspase 3 Antibody in Apoptosis Research
The caspases are a group of cysteine protease enzymes essential to apoptosis, inflammation and necrosis. Caspase 3 has been identified as one of the key mediators of apoptosis.Human caspases form three distinct groups: cytokine activators, which are...    Read more.
Pathway Highlight: Three key factors that contribute to cellular heterogeneity in apoptosis
Have you ever wondered why cells in the same population respond differently to an apoptotic stimulus? Apoptosis, a form of programmed cell death, is vital for the removal of unwanted or damaged cells. As with most cellular processes, too much or to...    Read more.
Bax Research Gives New Insight into Oxidative Apoptosis
Bax is a member of the Bcl-2 family; an extensive range of proteins which play key roles in apoptosis, or programmed cell death, by regulating outer mitochondrial membrane permeability. We at Novus Biologicals are one of the leading antibody suppliers...    Read more.
Mitofilin and the Mitochondrial Inner Membrane Organizing System (MINOS)
Mitofilin was originally described as a heart muscle protein due to its high expression in the heart. Recently, analysis of the human heart mitochondrial proteome demonstrated that Mitofilin is one of the most abundant mitochondrial proteins (1). Rese...    Read more.
Cytochrome C in Apoptosis, Immune Response and Cancer
Cytochrome C is an electron carrier protein that localizes in mitochondrion intermembrane space and has been identified as one of the key signaling molecules of apoptosis or programmed cell death. Suppression of the anti-apoptotic members or activatio...    Read more.
Cytochrome C - a mediator of apoptosis
Cytochrome C is a small heme protein within the inner mitochondrial membrane responsible for carrying electrons within the respiratory transport chain.  Additionally, cytochrome c has also been identified as a player in programmed cell death (apop...    Read more.
Bcl-2 - an antiapoptotic protein with an important role in cancer cell survival
B-cell lymphoma 2 (Bcl-2) protein is an oncogene that normally acts as an apoptotic inhibitor and localizes to the mitochondrial membrane where it prevents the release of cytochrome c. The Bcl-2 protein family consists of over 20 proteins each co...    Read more.
Read more Cytochrome c related blogs.