SIRT4 Products

Description

SIRT4 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

Bioinformatics

Entrez	23409 Human 75387 Mouse
Uniprot	EAW98182 Human NM_012240 Human NP_036372 Human NP_036372. Human NP_036372.1 Human
Product By Gene ID	23409
Alternate Names	EC 2.4.2.- EC 3.5.1 MGC130046 MGC130047 MGC57437 SIR2L4NAD-dependent ADP-ribosyltransferase sirtuin-4 sir2-like 4 SIR2-like protein 4 sirtuin (silent mating type information regulation 2 homolog) 4 (S. cerevisiae) sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 4 sirtuin 4 sirtuin type 4

Research Areas for SIRT4

Find related products by research area and learn more about each of the different research areas below.

DNA Repair
Epigenetics
Histone Deacetylases
Homologous Recombination