Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Pm
Applications: WB, ELISA, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
The sodium-potassium-chloride cotransporter isoform 2 is kidney-specific and is found on the apical membrane of the thick ascending limb of Henle's loop and the macula densa. It accounts for most of the NaCl resorption with the stoichiometry of 1Na:1K:2Cl and is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. [provided by RefSeq]
Bioinformatics
| Entrez |
Rat
Human
|
| Uniprot |
Human
Human
Human
Rat
Human
|
| Product By Gene ID |
6557 |
| Alternate Names |
- BSC1
- Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2
- Kidney-specific Na-K-Cl symporter
- MGC48843
- NKCC2A variant A
- NKCC2Na-K-2Cl cotransporter
- solute carrier family 12 (sodium/potassium/chloride transporters), member 1
- solute carrier family 12 member 1
|
