M-CSF Products

Description

M-CSF (macrophage colony stimulating factor, colony stimulating factor 1, CSF-1) is a hemtopoietic growth factor produced by monocytes, granulocytes, endothelial cells, fibroblasts and activated B-cells and T-cells. M-CSF stimulates macrophage colony formation and regulates proliferation and differentiation of hematopoeitic stem cells into macrophages and regulates survival and differentiation of monocytes. It enhances antibody-dependent cell-mediated cytotoxity, enhances marophage killing of tumor cells and microorganisms, regulates the release of cytokines and inhibits bone resorption by osteoclasts. Human M-CSF shows biological activity on murine and rat cells and although murine M-CSF is active in rat cells it is inactive in human cells.

Bioinformatics

Entrez	12977 Mouse 1435 Human
Uniprot	AAH21117 Human NM_000757 Human NM-172211 Human NP_000748 Human NP_000748.3 Human NP_757350 Human NP_757351 Human P09603 Human Q5VVF3 Human
Product By Gene ID	1435
Alternate Names	colony stimulating factor 1 (macrophage) CSF-1 Lanimostim macrophage colony stimulating factor macrophage colony-stimulating factor 1 M-CSF MCSFlanimostim MGC31930

Research Areas for M-CSF

Find related products by research area and learn more about each of the different research areas below.

Biologically Active Proteins
Cell Cycle and Replication
Cytokine Research
Stem Cell Markers

Related M-CSF Blog Posts

Check out the latest blog posts on M-CSF.

Toll-like receptors in the intestinal epithelial cells By Jamshed Arslan, Pharm. D., PhD. Toll-like receptors (TLRs) are microbe-sensing proteins that act as first responders to danger signals. TLRs help the intestinal epithelial cells (IECs) recognize commensal bacteria ...    Read more.

Read more M-CSF related blogs.