Species: Hu
Applications: WB, CyTOF-ready, Flow
Host: Goat Polyclonal
Species: Hu, Mu, Rt, Bv, Ch
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Description
GFI1 encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
|
| Product By Gene ID |
2672 |
| Alternate Names |
- GFI-1
- growth factor independence-1
- growth factor independent 1 transcription repressor
- growth factor independent 1
- Growth factor independent protein 1
- SCN2
- Zinc finger protein 163
- zinc finger protein Gfi-1
- ZNF163FLJ94509
|
Research Areas for GFI-1
Find related products by research area and learn more about each of the different research areas below.
Cell Cycle and Replication
![Intracellular Staining by Flow Cytometry GFI-1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/GFI1_AF3540_Flow_Cytometry_23623.jpg)
![Western Blot GFI-1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af3540_human-gfi-1-affinity-purified-polyclonal-ab-41202412394973.jpg)
![Western Blot GFI-1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af3540_human-gfi-1-affinity-purified-polyclonal-ab-41202412401266.jpg)
