Species: Mu
Applications: WB, IHC
Host: Goat Polyclonal
Species: Hu, Mu, Po, Bv, Rb
Applications: WB, ICC/IF, IHC, Func
Host: Rabbit Polyclonal
Species: Mu
Applications: WB
Host: Rat Monoclonal
Species: Mu
Applications: ELISA
Species: Rt
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Hu
Applications: WB
Species: Mu
Applications: Bioactivity
Species: Mu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Description
The GDF5 gene is involved in skeletal development through bone and cartilage formation. This gene encodes for a 501 amino acid long, 55 kDA protein that is part of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily which is known to regulate cell growth and differentiation in embryotic and adult tissues. The GDF5 gene is involved in paxillian interactions, mitochondrial apoptosis, the cytokine-cytokine receptor interaction, and the TGF-beta signaling pathway through interacting with other genes such as BMPR1A, BMPR1B, BMPR2, HTRA1, and CHRDL2. The GDF5 gene has been associated to chondrodysplasia, synostosis, periostitis, short stature, cushing's symphalangism, brachydactyly and ankylosis.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Mouse
Human
|
| Product By Gene ID |
8200 |
| Alternate Names |
- BMP14
- Cartilage-derived morphogenetic protein 1
- cartilage-derived morphogenetic protein-1
- CDMP-1
- CDMP1LAP4
- GDF-5
- growth differentiation factor 5
- growth/differentiation factor 5
- OS5
- radotermin
- Radotermin
- SYNS2
|
Research Areas for GDF-5/BMP-14
Find related products by research area and learn more about each of the different research areas below.
Cytokine Research
![Immunohistochemistry GDF-5/BMP-14 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/GDF-5_AF853_Immunohistochemistry_6908.jpg)
![Western Blot GDF-5/BMP-14 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/af853_mouse-gdf-5-affinity-purified-polyclonal-ab-western-blot-25102022133916.jpg)
![N/A GDF-5/BMP-14 [Biotin]](http://images.novusbio.com/fullsize2/DATA_GDF5_DY85305_ELISA_2547.jpg)
![Bioactivity GDF-5/BMP-14 [Unconjugated]](http://images.novusbio.com/fullsize2/GDF5_8340G5_1025.jpg)