Species: Hu
Applications: WB, Simple Western, Flow, CyTOF-ready
Host: Goat Polyclonal
Species: Hu
Applications: WB, ELISA, Func, IP, KD
Host: Mouse Monoclonal
Species: Hu
Applications: WB, IP
Host: Mouse Monoclonal
Species: Rt
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Po
Applications: ELISA, NULL
Species: Hu
Applications: Enzyme Activity
Species: Hu
Applications: Enzyme Activity
Species: Hu
Applications: AC
Description
Proteinase-activated receptor 3 (PAR3) is a member of the Proteinase-Activated Receptor subfamily. The enzyme thrombin is involved in the activation of platelets, leukocytes, endothelial cells, and mesenchymal cells at sites of vascular injury. These cellular responses are triggered through proteolytic activation of PAR3 and other receptors by thrombin. It is believed that PAR3 functions as a cofactor for the cleavage and activation of PAR4. PAR3 expression has been documented in blood, bone marrow, lung, spleen, and vessel. ESTs have been isolated from head/neck, skeletal muscle, and skin libraries.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
|
| Product By Gene ID |
2147 |
| Alternate Names |
- coagulation factor II (thrombin) receptor-like 2
- Coagulation factor II receptor-like 2 (protease-actovated receptor 3)
- Coagulation factor II receptor-like 2
- Coagulation Factor II
- PAR-3
- PAR3proteinase-activated receptor 3
- protease-activated receptor 3
- proteinase-activated receptor-3
- PT
- serine protease
- Thrombin receptor-like 2
|
![Western Blot Coagulation Factor II/Thrombin Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/af1148_human-factor-ii-thrombin-affinity-purified-polyclonal-ab-western-blot-1862021152049.jpg)
![Western Blot Coagulation Factor II/Thrombin Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/af1148_human-factor-ii-thrombin-affinity-purified-polyclonal-ab-western-blot-1862021152235.jpg)
![Flow Cytometry Coagulation Factor II/Thrombin Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/af1148_human-factor-ii-thrombin-affinity-purified-polyclonal-ab-flow-cytometry-662020193826.jpg)
![Flow Cytometry Coagulation Factor II/Thrombin Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Coagulation_Factor_II_AF1148_Flow_Cytometry_14472.jpg)
![Simple Western Coagulation Factor II/Thrombin Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Coagulation_Factor_II_AF1148_Simple_Western_17119.jpg)
![Western Blot Coagulation Factor II/Thrombin Antibody (200710) [Unconjugated] - Pro form](http://images.novusbio.com/fullsize/antibody/mab1473_human-pro-factor-ii-prothrombin-mab-clone-200710-western-blot-245202192541.jpg)
