Species: Hu
Applications: WB, ELISA, Flow, IHC, CyTOF-ready, MS
Host: Mouse Monoclonal
Species: Hu
Applications: WB, Flow, IHC, CyTOF-ready, ICC/IF
Host: Sheep Polyclonal
Species: Hu
Applications: WB, Flow, IHC, IP, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Host: Rabbit
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Pm-Cm
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Species: Mu
Applications: Bioactivity
Description
CD7, also known as gp40, is a 40 kD type I transmembrane glycoprotein member of the immunoglobulin superfamily. It is found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human Human |
Product By Gene ID |
924 |
Alternate Names |
- CD7 antigen (p41)
- CD7 antigen
- CD7 molecule
- GP40T-cell surface antigen Leu-9
- LEU-9
- T-cell antigen CD7
- T-cell leukemia antigen
- Tp40
- TP41p41 protein
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