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TNF-alpha

Unlocking the Potential of Biosimilars in Immuno-Oncology

By Jennifer Jones, M.S.

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Tired T cells: Hypoxia Drives T cell Exhaustion in the Tumor Microenvironment

By Hunter Martinez

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Immune Cell Metabolic Flux Influences Type I Diabetes

By Hunter Martinez

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Approved COVID-19 Vaccines: Delivery of Nucleic Acid Cargo and Immune Response

Banner image showing COVID-19 viruses with spike proteins.

By Jamshed Arslan, Pharm D, PhD

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Pattern recognition receptors (PRR) expression and function in endothelial cells

Banner image cartoon depicting a portion of the TLR signaling pathway.

By Victoria Osinski

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COVID-19-Related Neurological Problems: Uncovering the Mechanisms

Novus Biologicals 3D image for coronavirus banner

By Jamshed Arslan, Pharm D, PhD

Tags:

virology-bacteria-parasite

SARS-CoV-2 spike protein

neurodegeneration

blood brain barrier

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Liver ASK1 activates autophagy to protect against hepatic fat accumulation, non-alcoholic steatohepatitis and fibrosis

MAP3K9 a MAP3K family member is expressed in the cytoplasm of human liver hepatocytes.

By Jamshed Arslan, Pharm. D., PhD.

Tags:

lipopolysaccharide

collagen-i-alpha-1

Metabolic Syndrome: Symptoms and associated disease states

The term, metabolism, refers to the totality of chemical reactions that occur in a biological system for the conversion of ingested nutrients into their basic constituents (i.e. proteins, lipids, nucleic acids and carbohydrates).

Tags:

Lipid and Metabolism

adiponectin-acrp30

beta-3-adrenergic-r-adrb3

hormone-sensitive-lipase-hsl

glycogen-phosphorylase-muscle-form

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Increased wild type FUS levels in ALS patients lead to a toxic microenvironment and motor neuron neurodegeneration

Dual expression of ALDH1L1-red and Vimentin-green identifies astrocytes which may be identified by their golden or red fluorescence. ALDH1L1 is expressed in the cell body and processes of astrocytes.

By Michalina Hanzel, PhD

Tags:

neurodegeneration

Amyotrophic Lateral Sclerosis

il-1-beta-il-1f2

Michalina Hanzel

You complete me: Natural killer cells need TGF-beta inhibition to effectively combat cancers

By Jamshed Arslan Pharm.D.

Tags:

Natural Killer cells (NK)

Innate Immunity

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