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LC3-II

Liver ASK1 activates autophagy to protect against hepatic fat accumulation, non-alcoholic steatohepatitis and fibrosis

Autophagy and Metastasis

Optogenetic Control of Mitophagy: AMBRA1 based mitophagy switch

Autophagic flux: Is p62 a good indicator?

Best genes to knockout to control autophagic flux

The LC3 A, B, C’s and 1, 2, 3’s

Best way to quantitatively measure Autophagic Flux

Application Focus: I see an increase in LC3, now what?

Why LC3B Antibodies Make Ideal Autophagosomes Membrane Markers

The human form of microtubule-associated protein light chain 3 (LC3) is expressed as 3 splice variants LC3A, LC3B, and LC3C.1 LC3B is a subunit of the MAP1A and MAP1B microtubule-binding proteins and plays a central role in autophagosome membrane structure.

Three things everyone studying autophagy should know

Novus Biologicals' antibodies are the gold standard to monitor autophagy and detect LC3 expression. The recently published Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition) comprehensively details methods to monitor autophagy in cell or tissue samples. Importantly, these guidelines also provide key considerations for data interpretation and tips to creating better western blot data.  

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