Species: Hu
Applications: WB, Simple Western, ICC/IF
Host: Mouse Monoclonal
Species: Hu, Mu
Applications: WB, IHC, KD
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Ca, Eq
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: PAGE
Description
Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of ts function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
5925 |
| Alternate Names |
- OSRC
- osteosarcoma
- p105-Rb
- pp110
- pRb
- Rb
- RB
- retinoblastoma 1
- retinoblastoma suspectibility protein
- retinoblastoma-associated protein
|
![Western Blot RB1 Antibody (607121) [Unconjugated]](http://images.novusbio.com/fullsize2/RB1_MAB6495_Western_Blot_10216.jpg)
![Immunocytochemistry RB1 Antibody (607121) [Unconjugated]](http://images.novusbio.com/fullsize2/RB1_MAB6495_Immunocytochemistry_10464.jpg)
![Simple Western RB1 Antibody (607121) [Unconjugated]](http://images.novusbio.com/fullsize2/RB1_MAB6495_Simple_Western_16629.jpg)
![Western Blot RB1 Antibody (607121) [Unconjugated]](http://images.novusbio.com/fullsize/mab6495_human-rb1-mab-clone-607121-812025548577.jpg)
