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ZMPSTE24 Antibody Blocking Peptide

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications AC
Concentration
1.0 mg/ml

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ZMPSTE24 Antibody Blocking Peptide Summary

Description
A ZMPSTE24 antibody blocking peptide.
Specificity
This peptide is specific for NB100-2388 only.
Protein/Peptide Type
Antibody Blocking Peptide
Gene
ZMPSTE24

Applications/Dilutions

Dilutions
  • Antibody Competition
Application Notes
This peptide is useful as a blocking peptide for NB 100-2388. For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Peptide dissolved in dH2O. Contains no BSA.
Preservative
No Preservative
Concentration
1.0 mg/ml

Alternate Names for ZMPSTE24 Antibody Blocking Peptide

  • zona pellucida binding protein 2
  • zona pellucida-binding protein 2
  • ZPBP-like protein
  • ZPBPLMGC41930

Background

ZMPSTE24, also known as FACE1, is a zinc metalloprotease involved in the post-translational processing of Lamin A/C precursors. Specifically, ZMPSTE-24 proteolytically removes the C-terminal three residues of the farnesylated Lamin proteins.

FACE-1 is widely expressed, with the highest levels found in the kidney, prostate, testis and ovary.

Mutations in ZMPSTE24 have been associated with human diseases such as mandibuloacral dysplasia with type B lipodystrophy (MADB) and lethal tight skin contracture syndrome (LTSCS), often due to the accumulation of LMNA precursors. It is theorized that ZMPSTE24 may play an important role in human ageing, based on its association with LMNA.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Publications for ZMPSTE24 Protein (NB100-2388PEP) (0)

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FAQs for ZMPSTE24 Protein (NB100-2388PEP) (0)

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Additional ZMPSTE24 Products

Research Areas for ZMPSTE24 Protein (NB100-2388PEP)

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Blogs on ZMPSTE24.

ZMPSTE24 Mutations, Lamin A Processing & Laminopathies
ZMPSTE24 (FACE-1, CAAX prenyl protease 1 homolog) is a membrane associated zinc metalloprotease of the peptidase M48A family. It's catalytic activity can be defined as the peptide bond hydrolyzed in the sequence -C-|-A-A-X in which C is an S-isoprenyl...  Read full blog post.

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Bioinformatics

Gene Symbol ZMPSTE24