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XPF Antibody (OTI3H7) [Janelia Fluor® 585]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clone
OTI3H7
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 585

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-74882AF350
Alexa Fluor 405
NBP2-74882AF405
Alexa Fluor 488
NBP2-74882AF488
Alexa Fluor 532
NBP2-74882AF532
Alexa Fluor 594
NBP2-74882AF594
Alexa Fluor 647
NBP2-74882AF647
Alexa Fluor 700
NBP2-74882AF700
Alexa Fluor 750
NBP2-74882AF750
Allophycocyanin
NBP2-74882APC
Allophycocyanin/Cy7
NBP2-74882APCCY7
Biotin
NBP2-74882B
CoraFluor 1
NBP2-74882CL1
DyLight 350
NBP2-74882UV
DyLight 405
NBP2-74882V
DyLight 488
NBP2-74882G
DyLight 550
NBP2-74882R
DyLight 594
NBP2-74882DL594
DyLight 650
NBP2-74882C
DyLight 680
NBP2-74882FR
DyLight 755
NBP2-74882IR
FITC
NBP2-74882F
HRP
NBP2-74882H
Janelia Fluor 525
NBP2-74882JF525
Janelia Fluor 549
NBP2-74882JF549
Janelia Fluor 635
NBP2-74882JF635
Janelia Fluor 646
NBP2-74882JF646
Janelia Fluor 669
NBP2-74882JF669
PE
NBP2-74882PE
PE/Atto594
NBP2-74882PEATT594
PE/Cy5.5
NBP2-74882PECY55
PE/Cy7
NBP2-74882PECY7
PerCP
NBP2-74882PCP
Unconjugated
NBP2-45503
mFluor Violet 450 SE
NBP2-74882MFV450
mFluor Violet 500 SE
NBP2-74882MFV500
mFluor Violet 610 SE
NBP2-74882MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-45503
Azide and BSA Free
NBP2-74882
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XPF Antibody (OTI3H7) [Janelia Fluor® 585] Summary

Immunogen
Full length human recombinant protein of human ERCC4(NP_005227) produced in HEK293T cell.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ERCC4
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for XPF Antibody (OTI3H7) [Janelia Fluor® 585]

  • DNA excision repair protein ERCC-4
  • DNA repair protein complementing XP-F cells
  • EC 3.1
  • ERCC11
  • ERCC4
  • excision repair cross-complementing rodent repair deficiency, complementationgroup 4
  • xeroderma pigmentosum, complementation group F
  • XPF
  • XPFcomplementing defective, in Chinese hamster

Background

XPF/ERCC4 is suggested to play a role in the repair of DNA double-strand breaks (DSB), homologous recombination, and gene conversion via single-strand annealing (SSA). XPF/ERCC4 is an endonuclease that incises 5-prime DNA. Defects in XPF/ERCC4 cause xeroderma pigmentosum VI (XP6) an autosomal recessive disease characterized by hypersensitivity to sunlight and a predisposition to skin cancer as well as neurological abnormalities. Defects in XPF/ERCC4 are also responsible for XFE progeroid syndrome, a syndrome characterized by dwarfism, cachexia, and microcephaly.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ERCC4